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Record W4375851357 · doi:10.1101/2023.05.07.539751

Lateralized Neural Entropy modulates with Grip Force during Precision Grasping

2023· preprint· en· W4375851357 on OpenAlexaff
Nishant Rao, Andrew Paek, José L. Contreras-Vidal, Pranav J. Parikh

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2023
Typepreprint
Languageen
FieldNeuroscience
TopicEEG and Brain-Computer Interfaces
Canadian institutionsMcGill University
FundersEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentNational Institute of Child Health and Human DevelopmentNational Institutes of HealthUniversity of HoustonNational Science Foundation
KeywordsElectroencephalographyIsometric exerciseSample entropyPsychologyStandard deviationNeuroscienceAudiologyPhysical medicine and rehabilitationPattern recognition (psychology)MathematicsStatisticsCognitive psychologyMedicinePhysical therapy

Abstract

fetched live from OpenAlex

When holding a coffee mug filled to the brim, we strive to avoid spilling the coffee. This ability relies on the neural processes underlying the control of finger forces on a moment-to-moment basis. The brain activity lateralized to the contralateral hemisphere averaged over a trial and across the trials is known to be associated with the magnitude of grip force applied on an object. However, the mechanistic involvement of the variability in neural signals during grip force control remains unclear. In this study, we examined the dependence of neural variability over the frontal, central, and parietal regions assessed using noninvasive electroencephalography (EEG) on grip force magnitude during an isometric force control task. We hypothesized laterally specific modulation in EEG variability with higher magnitude of the grip force exerted during grip force control. We utilized an existing EEG dataset (64 channel) comprised of healthy young adults, who performed an isometric force control task while receiving visual feedback of the force applied. The force magnitude to be exerted on the instrumented object was cued to participants during the task, and varied pseudorandomly among 5, 10, and 15% of their maximum voluntary contraction (MVC) across the trials. We quantified neural variability via sample entropy (sequence-dependent measure) and standard deviation (sequence-independent measure) of the temporal EEG signal over the frontal, central, and parietal electrodes. The EEG sample entropy over the central electrodes showed lateralized, nonlinear, localized, modulation with force magnitude. Similar modulation was not observed over frontal or parietal EEG activity, nor for standard deviation in the EEG activity. Our findings highlight specificity in neural control of grip forces by demonstrating the modulation in sequence-dependent but not sequence-independent component of EEG variability. This modulation appeared to be lateralized, spatially constrained, and functionally dependent on the grip force magnitude. We discuss the relevance of these findings in scenarios where a finer precision is essential to enable grasp application, such as prosthesis and associated neural signal integration, and propose directions for future studies investigating the mechanistic role of neural entropy in grip force control.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.239
Teacher spread0.214 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2023
Admission routes1
Has abstractyes

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