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Record W4376527185 · doi:10.25236/fmsr.2023.050510

Meta-analysis of risk factors for carotid plaque formation in type 2 diabetes mellitus

2023· article· en· W4376527185 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueFrontiers in Medical Science Research · 2023
Typearticle
Languageen
FieldMedicine
TopicCardiovascular Disease and Adiposity
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineInternal medicineDiabetes mellitusMeta-analysisType 2 Diabetes MellitusInclusion and exclusion criteriaType 2 diabetesEndocrinologyPathology

Abstract

fetched live from OpenAlex

Objective: To investigate the risk factors of carotid artery plaque formation in type 2 diabetes mellitus in China through meta-analysis. Methods: The literature on the risk factors of carotid plaque formation in type 2 diabetes mellitus in China was retrieved from China Journal Full-text Database (CNKI), Wanfang Digital Journal Full-text Database (Wanfang), VIP journal Resource integration Service platform (VIP) and PubMed database. Newcastle-Ottawa Scale(NOS) used the most comprehensive case-control trial data collection to evaluate the quality of the literature excerpts combined with inclusion and exclusion criteria.Literatures with scores ≥7 were included in the study, and finally meta-analysis was conducted by RevMan5.4. Results: 32 literatures met the inclusion criteria, and the cumulative number of cases and controls were 5710 and 5405, respectively. The results of meta-analysis showed that the risk factors of carotid plaque formation in type 2 diabetes mellitus in China were as follows: Triglyceride (TG) (OR= 2.74, 95%CI: 2.25-3.33), total cholesterol (TC) (OR=2.50, 95%CI: 2.22-2.83), glycosylated hemoglobin (HbA1c) (OR=1.41, 95%CI:1.33 ~ 1.50), history of hypertension (OR=2.03, 95%CI:1.69 ~ 2.44), low density lipoprotein (LDL-C) (OR=1.64, 95%CI:1.31 ~ 2.06), age (OR=1.12, 95%CI:1.09 ~ 1.14), diabetes duration (OR=1.04, 95%CI:1.03 ~ 1.06), smoking (OR=1.30, 95%CI:1.18 ~ 1.44), systolic blood pressure (SBP) (OR=1.04, 95%CI:1.02 ~ 1.05). Conclusion: TG, TC, HbA1c, hypertension history, LDL-C, age, diabetes course, smoking and SBP are independent risk factors for carotid plaque formation in type 2 diabetes mellitus. Smoking cessation, balanced diet, prevention and active treatment of hypertension have great significance for the formation of carotid plaque in type 2 diabetes mellitus.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.010
metaresearch head score (Gemma)0.005
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.124
Threshold uncertainty score0.611

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0100.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.010
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.110
GPT teacher head0.395
Teacher spread0.285 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it