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Record W4376642978 · doi:10.1111/bjh.18870

Long non‐coding <scp>RNAs</scp> associated with transcriptomic signatures and treatment outcome in diffuse large B‐cell lymphoma

2023· letter· en· W4376642978 on OpenAlexafffundabout
Gerben Duns, Melanie Winkle, Lauren C. Chong, Daisuke Ennishi, Ryan D. Morin, Arjan Diepstra, David W. Scott, Joost Kluiver, Christian Steidl, Anke van den Berg

Bibliographic record

VenueBritish Journal of Haematology · 2023
Typeletter
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCancer-related molecular mechanisms research
Canadian institutionsSimon Fraser UniversitySpinal Cord Injury BCUniversity of British Columbia
FundersCanadian Institutes of Health Research
KeywordsTranscriptomeDiffuse large B-cell lymphomaLymphomaCancer researchMedicineComputational biologyBiologyInternal medicineGeneGene expressionGenetics

Abstract

fetched live from OpenAlex

The raw sequencing data were previously deposited in the European Genome-phenome Archive (EGA) under accession number EGAS00001002657.4 The data generated during the current study are available from the corresponding author on request. Permission to access the RNAseq data from the cohort described in Schmitz et al. was obtained through dbGAP (https://www.ncbi.nlm.nih.gov/gap/); data sets phs001444 and phs001184 (which is a substudy of phs001175).15 Appendix S1. Appendix S2. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.251
Teacher spread0.239 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2023
Admission routes3
Has abstractyes

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