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Record W4377232702 · doi:10.1371/journal.pgen.1010753

Taste and pheromonal inputs govern the regulation of time investment for mating by sexual experience in male Drosophila melanogaster

2023· article· en· W4377232702 on OpenAlexafffund
Seung Gee Lee, Dongyu Sun, Hongyu Miao, Zekun Wu, Changku Kang, Baraa Saad, Khoi-Nguyen Ha Nguyen, Adrian Guerra-Phalen, Dorothy Bui, Al-Hassan Abbas, Brian Trinh, Ashvent Malik, Mahdi Zeghal, Anne-Christine Auge, Md Ehteshamul Islam, Kyle Wong, Tiffany Stern, Elizabeth Lebedev, Thomas N. Sherratt, Woo Jae Kim

Bibliographic record

VenuePLoS Genetics · 2023
Typearticle
Languageen
FieldNeuroscience
TopicNeurobiology and Insect Physiology Research
Canadian institutionsCarleton UniversityUniversity of Ottawa
FundersNatural Sciences and Engineering Research Council of CanadaUniversity of California, San FranciscoMitacsNational Research Foundation of KoreaBurroughs Wellcome FundYonsei UniversityUniversity of TorontoNational Research FoundationUniversity of OttawaKorea Brain Research InstituteGwangju Institute of Science and TechnologyNvidiaKorea Research Institute of Bioscience and BiotechnologyHoward Hughes Medical Institute
KeywordsBiologyDrosophila melanogasterMatingAdaptation (eye)Drosophila (subgenus)MelanogasterAntagonistic CoevolutionSex pheromoneEvolutionary biologyNeuroscienceZoologySexual conflictGenetics

Abstract

fetched live from OpenAlex

Males have finite resources to spend on reproduction. Thus, males rely on a 'time investment strategy' to maximize their reproductive success. For example, male Drosophila melanogaster extends their mating duration when surrounded by conditions enriched with rivals. Here we report a different form of behavioral plasticity whereby male fruit flies exhibit a shortened duration of mating when they are sexually experienced; we refer to this plasticity as 'shorter-mating-duration (SMD)'. SMD is a plastic behavior and requires sexually dimorphic taste neurons. We identified several neurons in the male foreleg and midleg that express specific sugar and pheromone receptors. Using a cost-benefit model and behavioral experiments, we further show that SMD behavior exhibits adaptive behavioral plasticity in male flies. Thus, our study delineates the molecular and cellular basis of the sensory inputs required for SMD; this represents a plastic interval timing behavior that could serve as a model system to study how multisensory inputs converge to modify interval timing behavior for improved adaptation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.026
Threshold uncertainty score0.222

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.066
GPT teacher head0.300
Teacher spread0.234 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations32
Published2023
Admission routes2
Has abstractyes

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