Response to “Letter to the Editor Concerning ‘Simultaneous, Single-Particle Measurements of Size and Loading Give Insights into the Structure of Drug-Delivery Nanoparticles’”
Bibliographic record
Abstract
ADVERTISEMENT RETURN TO ISSUEPREVLetter to the EditorNEXTResponse to "Letter to the Editor Concerning 'Simultaneous, Single-Particle Measurements of Size and Loading Give Insights into the Structure of Drug-Delivery Nanoparticles'"Albert KamanziAlbert KamanziMichael Smith Laboratories, University of British Columbia, 2329 West Mall, Vancouver, BC V6T 1Z4, CanadaMore by Albert Kamanzihttps://orcid.org/0000-0002-6790-1140, Mark SuttonMark SuttonDepartment of Physics, McGill University, 3600 University, Montreal, QC H3A 2T8, CanadaMore by Mark Sutton, Fredrik HöökFredrik HöökDepartment of Physics, Chalmers University of Technology, SE-412 96 Gothenburg, SwedenMore by Fredrik Höökhttps://orcid.org/0000-0003-1994-5015, and Sabrina Leslie*Sabrina LeslieMichael Smith Laboratories, University of British Columbia, 2329 West Mall, Vancouver, BC V6T 1Z4, CanadaDepartment of Physics, University of British Columbia, 2329 West Mall, Vancouver, BC V6T 1Z4, Canada*Email: [email protected]More by Sabrina Lesliehttps://orcid.org/0000-0003-4336-0447Cite this: ACS Nano 2023, 17, 10, 8843–8846Publication Date (Web):May 23, 2023Publication History Received21 April 2023Published online23 May 2023Published inissue 23 May 2023https://doi.org/10.1021/acsnano.3c03606Copyright © Published 2023 by American Chemical SocietyRIGHTS & PERMISSIONSArticle Views601Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (2 MB) Get e-AlertscloseSUBJECTS:Aromatic compounds,Hydrocarbons,Imaging,Lipids,Nanoparticles Get e-Alerts
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.003 | 0.017 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.002 | 0.001 |
| Scholarly communication | 0.003 | 0.002 |
| Open science | 0.002 | 0.001 |
| Research integrity | 0.013 | 0.009 |
| Insufficient payload (model declined to judge) | 0.076 | 0.064 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".