Finnish Sauna Bathing and Vascular Health of Adults with Coronary Artery Disease: a Randomized Controlled Trial
Bibliographic record
Abstract
BACKGROUND: Regular Finnish sauna use has been associated with a reduced risk of cardiovascular mortality. However, physiological mechanisms underlying this association remain unknown. Other forms of heat therapy have been shown to improve markers of vascular health in healthy young adults, middle-aged adults with cardiovascular risk factors, and older adults with chronic heart failure. It is unknown if Finnish sauna use elicits similar adaptations. HYPOTHESIS: This study determined if Finnish sauna bathing improves markers of vascular health in adults with coronary artery disease (CAD). We tested the primary hypothesis that 8 weeks of Finish sauna bathing improves peripheral endothelial function. Secondary hypotheses were that Finish sauna bathing improves peripheral microvascular function, central arterial stiffness and blood pressure. METHODS: Forty-one adults (62 ± 6 years, 29.0 ± 4.3 kg/m2, 33 men/8 women) with stable CAD and naïve to heat therapy were randomized to 8 weeks of Finnish sauna use (n=21, 4 sessions/week, 20-30 min/session) or control intervention (lifestyle maintenance, n=20). Peripheral endothelial function (brachial artery flow-mediated dilation, FMD), central arterial stiffness (carotid-femoral pulse wave velocity), total (area under the curve) and peak post-occlusion forearm reactive hyperemia, and blood pressure (automated auscultation) were measured before and after the intervention. RESULTS: Brachial artery FMD changed from 4.09 ± 2.05% to 4.24 ± 2.70% in response to sauna bathing and from 4.00 ± 2.02% to 4.10 ± 2.10% in response to the control intervention (p for interaction = 0.95). The change in central arterial stiffness (p for interaction = 0.82), total reactive hyperemia (p for interaction = 0.07), systolic (p for interaction = 0.95) and diastolic (p for interaction = 0.29) blood pressure also did not differ between interventions. The change in peak reactive hyperemia differed between interventions (p for interaction = 0.05) due to a slight decrease in response to sauna bathing (3.03 ± 1.42 to 2.75 ± 1.18 ml/min/mmHg, p=0.76) relative to a slight increase in response to control (2.78 ± 0.98 to 3.24 ± 1.00 ml/min/mmHg, p=0.05). CONCLUSION: These results demonstrate that 4 sessions of Finnish sauna bathing per week for 8 weeks does not improve markers of vascular health in older adults with stable CAD. Heart and Stroke Foundation of Canada, Fonds de Recherche du Québec – Santé This is the full abstract presented at the American Physiology Summit 2023 meeting and is only available in HTML format. There are no additional versions or additional content available for this abstract. Physiology was not involved in the peer review process.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".