MétaCan
Menu
Back to cohort
Record W4378904074 · doi:10.1016/j.esmoop.2023.101567

The management of hepatocellular carcinoma. Current expert opinion and recommendations derived from the 24th ESMO/World Congress on Gastrointestinal Cancer, Barcelona, 2022

2023· review· en· W4378904074 on OpenAlexaff
Michel Ducreux, Ghassan K. Abou‐Alfa, Tanios Bekaii‐Saab, Jordan Berlin, Andrés Cervantes, Thierry de Baère, Charis Eng, Peter R. Galle, Sharlene Gill, Thomas Gruenberger, Karin Haustermans, Ángela Lamarca, Pierre Laurent‐Puig, Josep M. Llovet, F. Lordick, Teresa Macarulla, Deborah Mukherji, Kei Muro, Radka Obermannová, Juan Manuel O’Connor, Eileen M. O’Reilly, Pia Österlund, P. A. Philip, G. Prager, Erika Ruíz‐García, Bruno Sangro, Thomas Seufferlein, Josep Tabernero, Chris Verslype, Harpreet Wasan, Eric Van Cutsem

Bibliographic record

VenueESMO Open · 2023
Typereview
Languageen
FieldMedicine
TopicHepatocellular Carcinoma Treatment and Prognosis
Canadian institutionsUniversity of British Columbia
FundersAmgen Astellas BiopharmaChugai PharmaceuticalFlatiron HealthEMD SeronoAstraZenecaAlnylam PharmaceuticalsGenentechPancreatic Cancer Action NetworkIpsenSumitomo Dainippon Pharma OncologyNordic Pharma GroupFalk FoundationShionogiAstellas PharmaSamsungEisaiSirtex MedicalCancer Research UKPlexxikonSeagenGlaxoSmithKlineAdvanced Accelerator ApplicationsBeiGeneMomenta PharmaceuticalsDaiichi Sankyo EuropeAgios PharmaceuticalsMerck KGaAGilead SciencesTaiho PharmaceuticalRegeneron PharmaceuticalsMirati TherapeuticsBoston Scientific CorporationKaryopharm TherapeuticsArray BioPharmaExelixisCelgeneNational Cancer InstituteIncyteServierHalozymeKyowa Hakko KirinSanofiOno PharmaceuticalEli Lilly and CompanyBristol-Myers SquibbPfizerAmgenLes Laboratories Pierre Fabre
KeywordsHepatocellular carcinomaMedicineCirrhosisExpert opinionGastrointestinal cancerLiver cancerGeneral surgeryCancerInternal medicineIntensive care medicineGastroenterologyOncologyColorectal cancer

Abstract

fetched live from OpenAlex

This article summarises expert discussion on the management of patients with hepatocellular carcinoma (HCC), which took place during the 24th World Gastrointestinal Cancer Congress (WGICC) in Barcelona, July 2022. A multidisciplinary approach is mandatory to ensure an optimal diagnosis and staging of HCC, planning of curative and therapeutic options, including surgical, embolisation, ablative strategies, or systemic therapy. Furthermore, in many patients with HCC, underlying liver cirrhosis represents a challenge and influences the therapeutic options.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.007
Threshold uncertainty score0.022

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.002
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0070.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.224
GPT teacher head0.391
Teacher spread0.167 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations161
Published2023
Admission routes1
Has abstractyes

Explore more

Same venueESMO OpenSame topicHepatocellular Carcinoma Treatment and PrognosisFrench-language works237,207