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Record W4379193073 · doi:10.1093/jcag/gwad003

The 2023 Impact of Inflammatory Bowel Disease in Canada: Executive Summary

2023· review· en· W4379193073 on OpenAlexafffundabout
Joseph W. Windsor, M Ellen Kuenzig, Sanjay K. Murthy, Alain Bitton, Çharles N. Bernstein, Jennifer Jones, Kate Lee, Laura E. Targownik, Juan Nicolás Peña-Sánchez, Noelle Rohatinsky, Sara Ghandeharian, James Im, Tal Davis, Jake Weinstein, Quinn Goddard, Julia Gorospe, Eric I. Benchimol, Gilaad G. Kaplan

Bibliographic record

VenueJournal of the Canadian Association of Gastroenterology · 2023
Typereview
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicInflammatory Bowel Disease
Canadian institutionsPublic Health OntarioUniversity of SaskatchewanUniversity of CalgaryMount Sinai HospitalCrohn's and Colitis CanadaUniversity of ManitobaOttawa HospitalInstitute for Clinical Evaluative SciencesMcGill University Health CentreUniversity of OttawaUniversity of TorontoDalhousie UniversitySickKids Foundation
FundersCanadian Institutes of Health ResearchTakeda CanadaPfizer CanadaJanssen CanadaAmgen CanadaBristol-Myers Squibb CanadaSandoz CanadaCrohn's and Colitis CanadaPfizerHospital for Sick ChildrenMylanCanadian Association of GastroenterologyAbbVieUniversity of TorontoAbbVie CanadaAmgenBristol-Myers SquibbEli Lilly and CompanyDairy Farmers of Ontario
KeywordsMedicineInflammatory bowel diseaseDiseaseIndirect costsEpidemiologyPresenteeismUlcerative colitisEnvironmental healthDisease burdenGerontologyAbsenteeismInternal medicine

Abstract

fetched live from OpenAlex

The burden of inflammatory bowel disease (IBD) (i.e., associated direct and indirect costs, prevalence of disease, personal impact to the individual and to caregivers) continues to increase in Canada. The prevalence of IBD has increased since Crohn's and Colitis Canada's 2018 Impact of IBD report from an estimated 270,000 Canadians living with IBD in 2018 to an estimated 322,600 Canadians living with IBD today in 2023. Consequently, associated costs of IBD have also dramatically increased from an estimated $2.57 billion in 2018 to an estimated $5.38 billion in 2023; this increase is due to multiple factors including increased prevalence of disease, inflation, and additional identified factors (e.g., presenteeism, costs of childcare). Beyond the economic impact of IBD, these diseases have a significant impact on people living with the disease and their caregivers, including different presentations of disease, different commonly associated extra-intestinal manifestations or comorbid conditions, and different barriers to accessing care. In this supplementary issue, we review: Evolving trends in the epidemiology of IBD; updated estimates of indirect and direct costs (including out-of-pocket costs) associated with IBD; information specific to IBD in children, adolescents, and seniors; issues related to IBD pertaining to sex and gender; information specific to risks associated with COVID-19 and cancer related to IBD; an overview of current treatments for IBD; and evolving care models, including access to care.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.673
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.251
Teacher spread0.242 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations36
Published2023
Admission routes3
Has abstractyes

Explore more

Same venueJournal of the Canadian Association of GastroenterologySame topicInflammatory Bowel DiseaseFrench-language works237,207