P.138 Sphenoidal Sinus aspergillus infection presenting with right-sided painful ophthalmoplegia and cavernous sinus-orbital apex lesion: a case report.
Bibliographic record
Abstract
Background: Cavernous sinus-orbital apex aspergillosis is a rare but serious complication and difficult to diagnose based on clinical and radiological results. This condition is frequently diagnosed at a late stage because of its nonspecific and varying symptomatology, specifically in immuno-supressive patients. Early diagnosis and treatment is the key to prevent more serious central nerves system complications. Methods: We report the case of a 80-year-old man with a 2 month history of retroorbital pain before he developed a subacute cavernous sinus syndrome, with 3th cranial nerve palsy and right-sided painful ophthalmoplegia. Patient was on immune suppression therapy for chronic lymphocytic leukemia. Neuroimaging including CT scan and MRI suggested a malignant tumor involving the sphenoid sinus with extention to cavernous sinus-orbital ape. Results: The diagnosis of aspergillosis was made trans-sphenoidal approach and by histopathological examination. Soon after surgical drainage of the sphenoid sinus and systemic anti-fungal drug therapy, Both retroorbital pain resolved and cavernous sinus syndrome slowly start to recover. Conclusions: This case emphasizes the fact that invasive isolated sphenoid sinus aspergillosis must be considered in the list of lesions causing sinus cavernous syndrome and particularly in immune suppressed patients. Early diagnosis is the key to prevent more serious central nerves system complications.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.002 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.002 | 0.001 |
| Science and technology studies | 0.002 | 0.002 |
| Scholarly communication | 0.002 | 0.002 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.005 | 0.003 |
| Insufficient payload (model declined to judge) | 0.007 | 0.002 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".