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Record W4379348177 · doi:10.1017/cjn.2023.219

P.130 Efficacy of decompressive craniectomy after subarachnoid hemorrhage: a propensity-matched analysis of a South Australian Cerebrovascular Registry

2023· article· en· W4379348177 on OpenAlexvenueno aff
TJ O’Donohoe, Christopher D. Ovenden, George Bouras, Swathikan Chidambaram, AS Davidson, Timothy Kleinig, Amal Abou‐Hamden

Bibliographic record

VenueCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · 2023
Typearticle
Languageen
FieldMedicine
TopicTraumatic Brain Injury and Neurovascular Disturbances
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineSubarachnoid hemorrhageDecompressive craniectomyVasospasmPropensity score matchingClipping (morphology)Clinical endpointSurgeryAneurysmCohortAnesthesiaInternal medicineTraumatic brain injuryRandomized controlled trial

Abstract

fetched live from OpenAlex

Background: The efficacy of decompressive craniectomy (DC) for patients with intracranial hypertension secondary to aneurysmal subarachnoid haemorrhage (aSAH) remains unclear. Methods: We identified aSAH patients who underwent DC following microsurgical aneurysm repair from a prospectively maintained cerebrovascular registry and compared their outcomes with a propensity-matched cohort who did not. Results: A total of 45 aSAH patients underwent DC between 01/09/2011 and 20/07/2020 and were compared with 45 propensity-matched controls. There were no differences in patient age (p=0.48), gender (p=0.53) or the proportion requiring endovascular vasospasm treatment (p=1.00). However, patients in the DC subgroup had a higher mean WFNS grade (3.47±1.53) compared with matched controls (2.8±1.25, p=0.03). Patients treated with DC had a higher rate of inpatient mortality (20.00% vs 0.00%, p=0.0025), unfavourable outcome (mRS≥4) at 1st (42.22% vs 11.11%, p=0.0016) and final (31.11% vs 2.94%, p<0.001) follow-up, and NIS-Subarachnoid Hemorrhage Outcome Measure positivity (40.00% vs 13.33%, p=0.0079). They also had a higher median mRS at 1st [3(2–4) vs 1(1–2), p<0.001], and final [2(1–4 vs 1(1 (0–2), p<0.001] follow-up. Conclusions: Patients treated with DC fared worse at every endpoint, which was disproportionate to the difference in presenting WFNS grade. These data do not support the use of DC following microsurgical clipping of a ruptured aneurysm.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.014

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.002
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.040
GPT teacher head0.281
Teacher spread0.241 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

Explore more

Same venueCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques→Same topicTraumatic Brain Injury and Neurovascular Disturbances→French-language works237,207→