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Correlation of placental laterality and uterine artery Doppler in pre-eclampsia

2023· article· en· W4379536766 on OpenAlexaff
Sindhu Murali, Nandini Gopalakrishna, Jessica Fernandes, Krunal Nazareth

Bibliographic record

VenueInternational Journal of Reproduction Contraception Obstetrics and Gynecology · 2023
Typearticle
Languageen
FieldMedicine
TopicPregnancy and preeclampsia studies
Canadian institutionsASTER
Fundersnot available
KeywordsMedicineUterine arteryPlacentaEclampsiaPreeclampsiaObstetricsLateralityProspective cohort studyGestationPregnancyGynecologyFetusInternal medicineBiology

Abstract

fetched live from OpenAlex

Background: Pre-eclampsia is a complex condition associated with maternal and fetal mortality and morbidity. Various screening tests have been proposed for the prediction of pre-eclampsia with varying results. Non-invasive doppler velocimetry studies of uterine arteries in second trimester with abnormal forms can predict the occurrence of pre-eclampsia. This abnormal wave forms indicate defective uterine perfusion and is consequence of placental implantation laterally. The objective of this study was to correlate placental laterality and uterine artery doppler in pre-eclampsia. Methods: It was prospective study from November 2019 to March 2021 at M S Ramaiah medical college and hospitals, Bangalore. Results: In the present study, preeclampsia was seen in 36.5 % with lateral location of placenta, 19.3% with posterior location of placenta and 15.9% with anterior location of placenta. This was statistically significant with p<0.001. Uterine artery doppler, the pulsatality index (PI) was <95th centile in 88.1% and 11.9% had >95th centile The subjects with PI >95th centile, 65.5% developed preeclampsia and <95th centile, 13.1% developed pre-eclampsia. This was statistically significant. In this study, with PI at 1.68, the sensitivity was 53.19%, specificity was 92.86%, positive predictive value (PPV) of 64.1% and negative predictive value (NPV) was 89.2%. Conclusions: USG is a simple, non-invasive, easy to perform and cost-effective method to locate the placenta. Every attempt should be made to do Uterine artery doppler at the same sitting. Both these are non-invasive and can predict the occurrence of pre-eclampsia. These patients can be managed as high risk and monitored more carefully. Surveillance will help in decreasing maternal and perinatal mortality and morbidity.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.121
Threshold uncertainty score0.282

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.304
Teacher spread0.284 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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