Biomechanical Computational Study of Pedicle Screw Position and Density in Adolescent Idiopathic Scoliosis Instrumentation
Bibliographic record
Abstract
STUDY DESIGN: Computer simulation of adolescent idiopathic scoliosis instrumentation. OBJECTIVE: To test the hypothesis that different screw densities would result in different apical vertebral rotation (AVR) corrections and bone-screw forces in adolescent idiopathic scoliosis instrumentation. SUMMARY OF BACKGROUND DATA: The "Minimize Implants Maximize Outcomes" Clinical Trial revealed that the use of more versus fewer screws resulted in similar coronal plane correction for Lenke 1A curves. However, the biomechanical impact of screw density on transverse plane correction is still unclear. Further investigation is needed to determine if and how transverse plane correction is correlated with screw density. PATIENTS AND METHODS: We simulated apical vertebral derotation after segmental translation using patient-specific computer models of 30 patients from the "Minimize Implants Maximize Outcomes" Trial. For each case, 10 alternative screw patterns were tested with overall densities ranging between 1.2 and 2 screws per level fused, and local density at the 3 apical levels ranging between 0.7 and 2 (total: 600 simulations). Main thoracic (MT) Cobb angle, thoracic kyphosis (TK), AVR, and bone-screw forces were computed and compared. RESULTS: The presenting MT (62 ± 11°; range: 45° to 86°), TK (27 ± 20°; -5° to 81°), and AVR (14±7°; -2° to 25°) were corrected through segmental translation to 22 ± 7° (10° to 41°), 26 ± 5° (18° to 45°), and 14 ± 7° (-4° to 26°). After apical vertebral derotation, they became 16 ± 8° (1° to 41°), 24 ± 4° (13° to 40°), and 4 ± 5° (-12° to 18°). There was no significant difference in MT among screw patterns; higher screw density had lower bone-screw forces ( P < 0.05). The apical vertebral derotation maneuver reduced AVR by an average of 70%, positively correlated with apical screw density ( r = 0.825, P < 0.05). There was no significant difference in TK. CONCLUSION: Screw density had no significant effect on 3-dimensional correction through the primary segmental translation maneuver. Transverse plane correction through subsequent apical vertebral derotation was positively correlated with screw density at the apical levels ( r = 0.825, P < 0.05). Bone-screw forces were negatively correlated with overall screw density ( P < 0.05).
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.001 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".