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Record W4380224508 · doi:10.14740/wjon1596

The Association Between Oral Anaerobic Bacteria and Pancreatic Cancer

2023· review· en· W4380224508 on OpenAlexvenueno aff
Mesut Öğrendik

Bibliographic record

VenueWorld Journal of Oncology · 2023
Typereview
Languageen
FieldMedicine
TopicPancreatic and Hepatic Oncology Research
Canadian institutionsnot available
Fundersnot available
KeywordsPancreatic cancerMedicineAggregatibacter actinomycetemcomitansAnaerobic bacteriaPorphyromonas gingivalisPeriodontitisDysbiosisPancreatitisFusobacteriaPancreasInternal medicineGastroenterologyCancerAdenocarcinomaBacteriaProteobacteriaBiologyDisease

Abstract

fetched live from OpenAlex

Reports have shown increased positive correlations with the salivary microbiota and pancreatic carcinogenesis. A European study showed that high levels of Porphyromonas gingivalis were correlated with periodontium damage and were associated with a risk of pancreatic cancer (two-fold). A recent study, using oral mouthwash samples (n = 361 with pancreatic adenocarcinoma), determined that the presence of P. gingivalis and Aggregatibacter actinomycetemcomitans along with Fusobacteria and Leptotrichia were a risk factor for pancreatic cancer. The link between pancreatic cancer and periodontitis has been documented. Interestingly, periodontitis presents with inflammation and microbial dysbiosis, both of which have been characterized in pancreatic cancer. This review highlights multiple roles in which oral anaerobic bacteria can spread to the pancreas and contribute to pancreatic cancer. World J Oncol. 2023;14(3):174-177 doi: https://doi.org/10.14740/wjon1596

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.948
Threshold uncertainty score0.590

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0040.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.125
GPT teacher head0.461
Teacher spread0.336 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations13
Published2023
Admission routes1
Has abstractyes

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