Shorter duration of antibiotic therapy for exacerbation of COPD
Bibliographic record
Abstract
We would like to thank the authors of the recently released Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2023 report and express one area of concern related to the general recommendation for 5- to 7-day antibiotic therapy duration [1]. We believe the totality of evidence supports a shorter course (5 days or less) for treating mild to moderate exacerbations of COPD (ECOPD). Although longer courses of antibiotics have traditionally been recommended for many infections, the basis for this originated from dogma versus rigorous trial evidence [2]. Excessive antibiotic durations are not sustainable in the face of increasing antibiotic resistance, one of the top global public health threats. Highlighting the evidence that supports a more explicit statement recommending shorter duration of antibiotics for exacerbation of COPD http://bit.ly/3KmLmQR
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.021 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.002 | 0.001 |
| Scholarly communication | 0.001 | 0.002 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.018 | 0.018 |
| Insufficient payload (model declined to judge) | 0.010 | 0.009 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".