Eficacia de las células estromales mesenquimales (MSC) como tratamiento para pacientes con enfermedad obstructiva crónica (EPOC): Revisión Sistemática
Bibliographic record
Abstract
Objetivo: Determinar la eficacia del tratamiento con células estromales mesenquimales (MSC), en pacientes con enfermedad pulmonar obstructiva crónica (EPOC). Materiales y métodos: Análisis descriptivo, corte transversal, orientado hacia una revisión sistemática de artículos en inglés, publicados durante los últimos 6 años, en bases de datos como: PubMed, ScienceDirect, ClinicalTrials.gov; a través del uso de descriptores (DeCS) y operadores booleanos como: “Mesenchymal Stromal Cells¨ AND ¨Therapy¨ AND ¨COPD¨. Resultados: Se determinó que las MSC son prometedoras para aplicaciones terapéuticas en EPOC, dada la facilidad para obtenerlas, su escasa inmunogenicidad, sus propiedades reparadoras tisulares e inmunomodulación. Conclusiones: El éxito de esta terapia a las semanas o meses de la terapia con MSC, van a depender de la fase de la enfermedad, la presencia de exacerbaciones y factores de riesgo asociados a cada paciente.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.007 | 0.011 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.002 |
| Bibliometrics | 0.002 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.002 | 0.001 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".