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Pharmacological interventions and hormonal therapies for depressive symptoms in peri- and post-menopausal women: a network meta-analysis of randomized controlled trials

2023· article· en· W4381033777 on OpenAlexaff
Ping‐Tao Tseng, Hsien‐Jane Chiu, Mein‐Woei Suen, Bing‐Syuan Zeng, Ming‐Kung Wu, Yu‐Kang Tu, Kuo‐Chuan Hung, Yi‐Cheng Wu, Kuan‐Pin Su, Dian‐Jeng Li, Tien‐Yu Chen, Brendon Stubbs, André F. Carvalho, Marco Solmi, Trevor Thompson, Maria Gabriella Caruso, Yutaka Matsuoka, Yen‐Wen Chen, Pao‐Yen Lin, Cheuk‐Kwan Sun, Yu‐Shian Cheng, Yow‐Ling Shiue

Bibliographic record

VenuePsychiatry Research · 2023
Typearticle
Languageen
FieldMedicine
TopicMenopause: Health Impacts and Treatments
Canadian institutionsOttawa HospitalUniversity of Ottawa
FundersE-Da HospitalMinistry of Science and Technology, TaiwanTainan Municipal An-Nan HospitalChina Medical University, TaiwanChina Medical University Hospital
KeywordsMedicineRandomized controlled trialFluoxetineDepression (economics)MenopauseHormone replacement therapy (female-to-male)PlaceboMeta-analysisInternal medicineSubgroup analysisHormone therapyConfidence intervalGynecologyTestosterone (patch)Breast cancerAlternative medicine

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Direct model labels (unvalidated)

Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.

Model armCategoriesStudy designConfidence
gemmano category
Domain: not available · Genre: Empirical
About the Canadian research system: no · About a Canadian topic: no
Meta-analysishigh
gptno category
Domain: not available · Genre: Review
About the Canadian research system: no · About a Canadian topic: no
Meta-analysishigh
models agreeAgreement compares identical category sets and study designs across arms.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.020
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.281
Threshold uncertainty score0.706

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0200.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0060.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.284
GPT teacher head0.517
Teacher spread0.233 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Labeled directly by 2 models reading the full record.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreEmpirical · Review

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations28
Published2023
Admission routes1
Has abstractno

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