Psychosocial Factors, Pro-Inflammatory Markers & Serum Lipids among Patients with Suicidal Ideation & Suicidal Attempts
Bibliographic record
Abstract
Background: Suicide is a worldwide serious problem. It is a leading cause of death, accounting for 1.3% of all deaths worldwide in 2019 and Approximately 703,000 people die by suicide every year. We aimed to study the personal, cognitive, psychosocial, personality traits, psychopathological, pro-inflammatory markers & serum lipids differences between patients with suicidal ideation and patients with suicidal attempts and to assess predictor factors that make suicidal ideation convert to suicidal attempt.
 Subjects and Methods: This cross-sectional case control study was carried on participant aged 18 – 50 years, both sexes. Suicidal behavior of the study sample was assessed using Beck Scale for Suicidal Ideation (BSSI) & participants were classified into three equal groups according to their score in BSSI and their history of recent suicidal attempt (suicidal ideation group, suicidal attempt group & control group). Participants’ sociodemographic data were evaluated by a questionnaire designed by the researcher and reviewed by experts. Psychiatric assessment was done using the Mini-International Neuropsychiatric Interview (MINI). Socioeconomic status & cognitive functions were assessed by the socioeconomic status scale for health research in Egypt & the Montreal Cognitive Assessment (MoCA) test, respectively. Personality was assessed by short form of EPQ-R (Revised Eysenck Personality Questionnaire). Assessment of impulsivity & stress were done by using the Barratt Impulsiveness Scale (BIS-11) & the Hassles and Uplifts Scale (HUS), respectively. Hamilton Depression Rating Scale (HAM-D), Hamilton Anxiety Rating Scale (HAM-A) & the Positive and Negative Syndrome Scale (PANSS) were applied to determine the symptom severity in those diagnosed with depressive, anxiety & psychotic disorders.
 Results: Suicidal ideations & attempts were more common among psychiatric patients especially those suffering from depression. Suicidal behavior was associated with increased severity of depressive & anxiety symptoms. The most common method of suicidal attempts among females was drug overdose, while males used self-poisoning as the most popular method in attempting suicide. Risk of suicidal ideation & attempts increased in the following situations: younger age groups especially below 35 years, female gender, substance abuse, low socioeconomic level, past history & family history of suicidal behavior, neuroticism, psychoticism & introversion personality traits, impulsivity, high daily stress levels, increase in the severity of depressive & anxiety disorders, elevated [ESR, Hs-CRP & IL-6], lowered [total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL) & triglycerides (TG)]. The following factors protected from suicidal behaviors: marriage, work and having jobs, Family and social support, playing sports, having hobbies & higher socioeconomic levels.
 Risk factors for transition of participants from suicidal ideation to suicidal attempt included female gender, being unmarried & unemployed, low socioeconomic level, poor social support, past history of suicidal behavior, neuroticism personality traits, impulsivity, high stress levels, depressive disorders, elevated [Hs-CRP & IL-6], and low [TC, LDL & TG]. Protective factors against transition from suicidal ideation to attempt included playing sports & extraversion personality traits.
 Conclusion: The problem of suicide is a frequent and a multifaceted problem among the general population.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.003 | 0.014 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".