Metabolic and transcriptomic response of two juvenile anadromous brook charr (<i>Salvelinus fontinalis</i>) genetic lines towards a chronic thermal stress
Bibliographic record
Abstract
Many salmonid species are particularly susceptible to chronic and acute temperature changes caused by global warming. We aimed to study the differences in metabolic and transcriptomic responses of a chronic heat stress on a control and selected (absence of early sexual maturation and growth) line of brook charr Salvelinus fontinalis (Mitchill, 1814). We exposed individuals to different temperatures for 35 days (15, 17, and 19 °C). High temperature reduced the growth rate (in length) and the Fulton condition factor. Both maximal metabolic rate and the aerobic scope were higher in fish reared at 17 °C, while they decreased in fish maintained at 19 °C. The relative gene expression of cytochrome c oxidase was lower at 19 °C than at 15 °C. The relative gene expressions of both liver and gill hsp90 was higher at the highest temperature. The standard metabolic rate, while not affected by temperature, was higher for the control line over the selected line. Only in the control line, the relative expression of catalase and of receptor of insulin-like growth factor-1 increased at 19 °C. Our results showed that the selected line was able to cope more effectively with the oxidative stress caused by the rise in temperature.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".