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Record W4383683897 · doi:10.58931/cpct.2023.115

Update in the Management and Treatment of Adult Asthma for Primary Care Physicians

2023· article· en· W4383683897 on OpenAlexaffabout
Alan Kaplan

Bibliographic record

VenueCanadian Primary Care Today · 2023
Typearticle
Languageen
FieldMedicine
TopicAsthma and respiratory diseases
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsMedicineAsthmaIntensive care medicineInhaled corticosteroidsB2 receptorDiseasePrimary carePopulationAsthma managementDisease managementPediatricsInternal medicineFamily medicineEnvironmental health

Abstract

fetched live from OpenAlex

Asthma is a common illness; estimates are that it affects up to 18% of the global population, with rates increasing every year. Approximately 3.8 million Canadians have asthma, and these patients continue to suffer from inadequately controlled disease as well as exacerbations. Although we have more medication choice than ever, mortality rates in Canada have not declined. Our current pharmacologic strategy has been mostly unchanged for years; it starts with an anti-inflammatory medication, usually an inhaled corticosteroid (ICS) to treat the type 2 (T2) inflammation that is most common. When an ICS provides inadequate control, therapy is often stepped up to include an ICS/long-acting beta-agonist (LABA) combination and even additional therapies like leukotriene receptor antagonists or long-acting muscarinic agents (LAMAs). As patients with uncontrolled asthma are at risk for deleterious outcomes, controlling the disease and preventing exacerbations should be the goal for all patients.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.011
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.082
Threshold uncertainty score0.163

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.011
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0040.003
Science and technology studies0.0010.001
Scholarly communication0.0020.002
Open science0.0020.001
Research integrity0.0060.005
Insufficient payload (model declined to judge)0.0170.007

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.231
Teacher spread0.223 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2023
Admission routes2
Has abstractyes

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