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Record W4384562103 · doi:10.54097/hset.v54i.9783

Relationship between circadian disturbance and hypertension

2023· article· en· W4384562103 on OpenAlexaff
Yinuo Cai

Bibliographic record

VenueHighlights in Science Engineering and Technology · 2023
Typearticle
Languageen
FieldNeuroscience
TopicCircadian rhythm and melatonin
Canadian institutionsMaple Leaf Foods
Fundersnot available
KeywordsCircadian rhythmBlood pressureMelatoninMedicinePineal glandInternal medicineRenin–angiotensin systemEssential hypertensionAldosteroneEndocrinologyPhysiology

Abstract

fetched live from OpenAlex

According to the largest survey of its kind to date, since 1990, the number of 30-to 79-year-olds with hypertension has increased rapidly from 650 million to 1.28 billion. Although this number is rising rapidly, no one knows what causes blood pressure to rise. The cause of hypertension is still unclear. The factors that contribute to elevated blood pressure are numerous and confusing. Studies have shown that abnormal biological rhythms can lead to hypertension. One of the key factors contributing to elevated blood pressure is an abnormal biorhythm. It has also been shown that abnormal biological rhythms can lead to hypertension. The nervous system, the renin-angiotensin-aldosterone pathway and melatonin secretion from the pineal gland may all be affected by circadian rhythm problems, which in turn affects glucocorticoid-mediated hypertension, and thus the development and progression of hypertension. The current intervention of it mainly based on pharmacological therapy, supplemented by improvement of lifestyle habits. Several new strategies for the treatment of hypertension have emerged in recent years. For example, acupuncture needle treatment, melatonin promotion treatment, RDN treatment hair etc. This study will present these methods and experiments to draw conclusions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.747
Threshold uncertainty score0.369

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.003
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.240
Teacher spread0.212 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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