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Record W4384701289 · doi:10.1016/j.envres.2023.116681

Exposure to secondhand and thirdhand smoke in private vehicles: Measurements in air and dust samples

2023· article· en· W4384701289 on OpenAlexfundno aff
Xavier Continente, Elisabet Henderson, Laura López-González, Olena Tigova, Sean Semple, Rachel O’Donnell, Ana Navas‐Acién, Núria Cortés-Francisco, Noelia Ramírez, María José López, Yolanda Castellano, Marcela Fu, Montse Ballbè, Beladenta Amalia, Teresa Arechávala, Silvano Gallus, Alessandra Lugo, Xiaoqiu Liu, Elisa Borroni, Chiara Stival, Paolo Colombo, Luke Clancy, Sheila Keogan, Hannah Byrne, Panagiotis Behrakis, Anna Tzortzi, Constantine Vardavas, Vergina Konstantina Vyzikidou, Gerasimos Bakelas, George Mattiampa, Roberto Boffi, Ario Ruprecht, Cinzia De Marco, Alessandro Borgini, Chiara Veronese, Martina Bertoldi, Andrea Tittarelli, Giuseppe Gorini, Giulia Carreras, Barbara Cortini, Simona Verdi, Alessio Lachi, Elisabetta Chellini, Ángel López Nicolás, Marta Trapero‐Bertran, Daniel Celdrán Guerrero, Cornel Radu-Loghin, Dominick Nguyen, Polina Starchenko, Joan B. Soriano, Julio Ancochea, Tamara Alonso, María Teresa Pastor, Marta Erro, Ana Pilar Nso‐Roca, Patricia Pérez, Elena García Castillo

Bibliographic record

VenueEnvironmental Research · 2023
Typearticle
Languageen
FieldMedicine
TopicSmoking Behavior and Cessation
Canadian institutionsnot available
FundersFederación Española de Enfermedades RarasAgència de Gestió d'Ajuts Universitaris i de RecercaGeneralitat de CatalunyaEuropean Regional Development FundUniversity of StirlingEuropean CommissionHorizon 2020Terry Fox Research InstituteCentres de Recerca de CatalunyaPublic Health AgencyInstituto de Salud Carlos IIIIstituto di Ricerche Farmacologiche Mario Negri - IRCCSHORIZON EUROPE Framework ProgrammeUniversidad Politécnica de Cartagena
KeywordsCotinineInterquartile rangeNicotineSecondhand smokeThird-hand smokeMedicineTobacco smokeSmokeEnvironmental healthToxicologyAnimal scienceCigarette smokeInternal medicineSidestream smokeMeteorologyGeography

Abstract

fetched live from OpenAlex

This study aimed to estimate airborne nicotine concentrations and nicotine, cotinine, and tobacco-specific nitrosamines (TSNAs) in settled dust from private cars in Spain and the UK. We measured vapor-phase nicotine concentrations in a convenience sample of 45 private cars from Spain (N = 30) and the UK (N = 15) in 2017–2018. We recruited non-smoking drivers (n = 20), smoking drivers who do not smoke inside the car (n = 15), and smoking drivers who smoke inside (n = 10). Nicotine, cotinine, and three TSNAs (NNK, NNN, NNA) were also measured in settled dust in a random subsample (n = 20). We computed medians and interquartile ranges (IQR) of secondhand smoke (SHS) and thirdhand smoke (THS) compounds according to the drivers’ profile. 24-h samples yielded median airborne nicotine concentrations below the limit of quantification (<LOQ) (IQR:<LOQ- < LOQ) in non-smokers’ cars, 0.23 μg/m3 (IQR:0.18–0.45) in cars of smokers not smoking inside, and 3.53 μg/m3, (IQR:1.74–6.38) in cars of smokers smoking inside (p < 0.001). Nicotine concentrations measured only while travelling increased to 21.44 μg/m3 (IQR:6.60–86.15) in cars of smokers smoking inside. THS concentrations were higher in all cars of smokers, and specially in cars of drivers smoking inside (nicotine: 38.9 μg/g (IQR:19.3–105.7); NNK: 28.5 ng/g (IQR:26.6–70.2); NNN: 23.7 ng/g (IQR:14.3–55.3)), THS concentrations being up to six times those in non-smokers’ cars. All cars of smokers had measurable SHS and THS pollution, the exposure levels were markedly higher in vehicles of drivers where smoking took place. Our results evidence the need for policies to prohibit smoking in vehicles, but also urge for more comprehensive strategies aiming towards the elimination of tobacco consumption.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.012
Threshold uncertainty score0.024

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.167
GPT teacher head0.378
Teacher spread0.211 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations8
Published2023
Admission routes1
Has abstractyes

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