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Record W4385065870 · doi:10.21203/rs.3.rs-3178116/v1

The association of dietary glycemic index and glycemic load with risk of irritable bowel syndrome

2023· preprint· en· W4385065870 on OpenAlexaff
Mahnaz Reisian, Alireza Milajerdi, Ammar Hassanzadeh Keshteli, Fatemeh Abbası, Fahimeh Haghighatdoost, Leila Azadbakht, Ahmad Esmaillzadeh, Peyman Adibi

Bibliographic record

VenueResearch Square · 2023
Typepreprint
Languageen
FieldMedicine
TopicGastrointestinal motility and disorders
Canadian institutionsUniversity of Alberta
FundersIsfahan University of Medical Sciences
KeywordsIrritable bowel syndromeGlycemic loadMedicineInternal medicineConstipationOdds ratioGlycemic indexConfoundingGastroenterologyDiarrheaDietary fiberGlycemicFood frequency questionnaireFood scienceInsulin

Abstract

fetched live from OpenAlex

Abstract Purpose To date, no existing research has explored the potential relationship between dietary Glycemic Index (GI) and Glycemic Load (GL) and the risk of developing Irritable Bowel Syndrome (IBS). Our objective was to examine this association within a substantial sample of Iranian adults. Method This study was conducted on 3363 general public adults in Isfahan, Iran. A validated dish-based 106-item semi-quantitative food frequency questionnaire was used to examine dietary GI and GL. The presence of IBS was explored using a modified Persian version of the ROME III questionnaire. Totally, 22.2% (n = 748) of study participants had IBS. Result Participants with the highest dietary GI, had higher odds for IBS than those in the lowest category (OR: 1.34; 95% CI: 1.03–1.75). However, the association became non-significant after controlling for potential confounders (OR: 1.14; 95% CI: 0.81–1.61). A positive significant association was found between dietary GI and odds of IBS-constipation predominant (IBS-C) (OR: 1.96; 95% CI: 1.09–3.52), but not with IBS-diarrhea predominant (IBS-D) (OR: 0.78; 95% CI: 0.43–1.40). Conclusions No substantial link was observed between dietary glycemic load (GL) and the risk of overall irritable bowel syndrome (IBS) or its subtypes. However, a positive correlation was discovered between dietary GI and IBS with constipation (IBS-C).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.039
GPT teacher head0.336
Teacher spread0.297 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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