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Record W4385377493 · doi:10.1177/19714009231193161

Increased rate of significant findings on brain MRI during the early stage of the COVID-19 pandemic

2023· article· en· W4385377493 on OpenAlexaff
Matthias Wagner, Dalia A. Jadkarim, Nikil K Rajani, Asthik Biswas, Richard Olatunji, Wyanne Law, Logi Vidarsson, Afsaneh Amirabadi, Birgit Ertl‐Wagner

Bibliographic record

VenueThe Neuroradiology Journal · 2023
Typearticle
Languageen
FieldMedicine
TopicCOVID-19 and healthcare impacts
Canadian institutionsUniversity of CalgaryHospital for Sick ChildrenUniversity of Toronto
FundersNational Cancer Institute
KeywordsMedicinePandemicAbnormalityCoronavirus disease 2019 (COVID-19)NeuroimagingPediatricsInternal medicineDiseasePsychiatry

Abstract

fetched live from OpenAlex

Objectives To assess the effect of the COVID-19 pandemic on the proportion of abnormal paediatric neuroimaging findings as a surrogate marker for potential underutilisation. Methods Consecutive paediatric brain MRIs performed between March 27th and June 19th 2019 (T baseline ) and March 23rd and June 1st 2020 (T pandemic ) were reviewed and classified according to presence or absence and type of imaging abnormality, and graded regarding severity on a 5-point Likert scale, where grade 4 was defined as abnormal finding requiring non-urgent intervention and grade 5 was defined as acute illness prompting urgent medical intervention. Non-parametric statistical testing was used to assess for significant differences between T pandemic vs. T baseline . Results Fewer paediatric MRI brains were performed during T pandemic compared to T baseline (12.2 vs 14.7 examinations/day). No significant difference was found between the two time periods regarding sex and age (T baseline : 557 females (44.63%), 7.95 ± 5.49 years, T pandemic : 385 females (44.61%), 7.64 ± 6.11 years; p = 1 and p = .079, respectively). MRI brain examinations during T pandemic had a higher likelihood of being abnormal, 41.25% vs. 25.32% ( p<.0001). Vascular abnormalities were more frequent during T pandemic (11.01% vs 8.01%, p = .02), congenital malformations were less common (8.34% vs 12.34%, p = .004). Severity of MRI brain examinations was significantly different when comparing group 4 and group 5 individually and combined between T baseline and T pandemic ( p = .0018, p < .0001, and p <.0001, respectively). Conclusions The rate of abnormality and severity found on paediatric brain MRI was significantly higher during the early phase of the pandemic, likely due to underutilisation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.005
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.343
Threshold uncertainty score0.615

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.092
GPT teacher head0.373
Teacher spread0.281 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2023
Admission routes1
Has abstractyes

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