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Prevalence and predictive role of hypertriglyceridemia in statin-treated patients at very high risk: Insights from the START study
Leonardo De Luca, Pier Luigi Temporelli, Michele Massimo Gulizia, Lucio Gonzini, T Ammaturo, Luigi Tedesco, Silvia Pede, Fabrizio Oliva, Domenico Gabrielli, Furio Colivicchi, Maurizio Averna, Carmine Riccio, Antonio Francesco Amico, Dario Formigli, Girolamo Geraci, Andrea Di Lenarda, Aldo P. Maggioni, Donata Lucci, Andrea Lorimer, G Orsini, Gianna Fabbri, P. Priami, Patrizia Maras, Federica Ramani, Colomba Falcone, Ilaria Passarelli, Silvia Mauri, Paolo Calabrò, Renatomaria Bianchi, Gaetano Di Palma, F Mascia, Alfredo Vetrano, Adelaide Fusco, E Proia, Alessandro Aiello, Fabrizio Tomai, R. Licitra, Alessandro Petrolini, B. Bosco, F Magliari, M Callerame, T Mazzella, G.V. Lettica, Gianluca Lo Coco, F Incao, Lina Marinacci, S D‘Addario, Sara Tartaglione, S. Ubaldi, Federico Ariel Sànchez, Paolo Costa, Giuseppe Manca, Michelle D. Failla, Marino Scherillo, Vincenza Procaccini, Michele Senni, E M Luminita, Paolo Bonomo, C Mossa, Stefano Corda, Angela Rita Colavita, G Trevisonno, Giampiero Vizzari, Nicola Cosentino, C Formaro, Claudio Paolillo, I L Nalin, Francesco Mario De Rosa, F Fontana, G.F. Fuscaldo, E. Passamonti, E. Bertella, Elva Calvaruso, Elisabetta Varani, F Tani, Giordano Cicchitelli, P Paoloni, Alessandro Marziali, Gianluca Campo, Matteo Tebaldi, Simone Biscaglia, Matteo Di Biase, Natale Daniele Brunetti, Andrea Gallotta, Luisa Mattei, R. Marini, F. Balsemin, Maurizio Urbano, Rita Naio, Paolo Vicinelli, Giuseppe Arena, Maria Cristina Ritter Mazzini, N Gigli, Bruna Miserrafiti, Angela Monopoli, Andrea Mortara, Pietro Delfino, Margherita Chioffi, Paolo Marino, Miriam Gravellone, Lucas Regatieri Barbieri, Antonietta Ledda, Giulio Geraci, Maria Gabriella Carmina, A Raisaro, C. Di Giacomo, Alberto Somaschini, M.L. Fasano, M Sannazzaro, Romano Arcieri, M. Pantaleoni, Chiara Leuzzi, Giulia Gorlato, Gabriella Greco, A Chiera, Giovanni Malanchini, Maria P. Corral, Letizia Tedesco, Loredana Urso, Federico Piscione, Gennaro Galasso, Stefano Provasoli, Luciano Fattore, Giulia Lucca, Alberto Cresti, A. Cardillo, Maria Stella Fera, F Vennettilli, Carlo Gaudio, Vincenzo Paravati, Pasquale Caldarola, Nicola Locuratolo, Roberto Verlato, Fabio Conti, Giovanni Turiano, George Preti, Luciano Moretti, Simona Silenzi, Giovanni Colonna, A Picciolo, Antonino Nicosia, C Cascone, Germano Di Sciascio, Fabio Mangiacapra, Antonio Russo, Sandra Mastroianno, Giovanni Esposito, F Cosmi, Simona D’Orazio, Costantino Costantini, Alessia Lanari, Pasquale De Rosa, Luigi Esposito, Claudio Bilato, Chiara Dalla Valle, Monica Ceresa, Elena Colombo, Vincenzo Pennisi, G. Casciola, Mauro Driussi, Teodoro Bisceglia, Simonetta Scalvini, Francesca Rivadossi, Massimo Volpe, Filomena Comito, D Scorzoni, Paola Grimoldi, Rocco Lagioia, D Santoro, Nicoletta De Cesare, T. Comotti, Arnaldo Poli, Patera Martina, Maria Musolino, E I Multari, G Bilardo, G. Scalchi, Carla Olivieri, Fiorella Caranci, Daniela Pavan, Giuseppe Ganci, Andrea Mariani, Elena Falchetti, Tonino Lanzillo, Antonio Caccavale, Angelo Sante Bongo, Alessandro Rizzi, Roberto Favilli, Silvia Maffei, M Mallardo, Cosimo Fulgione, F. Bordin, Roberto Bonmassari, Elisa Battaia, A Puzzo, G. Vianello, Alessandro D’Arpino, M. Romei, Giuseppe Pajes, S Petronzelli, Fabio Ghezzi, Silvana Brigido, L. Pignatelli, Elvis Brscic, P Sori, Michael F Russo, E. Biancolillo, G Ignone, Nicholas A. Giorgio, C. Campaniello, P. Ponticelli, Alberto Margonato, Silvia Gerosa, A Cutaia, Calogero Casalicchio, Francesco Bartolomucci, Claudio Larosa, T Spadafina, Antonella Putignano, Raimondo De Cristofaro, Livia Bernardi, Luigi Sommariva, Andrea Celestini, C Bertucci, Maria Francesca Marchetti, Enrico Franceschini Grisolia, C Ammendolea, Marco Carini, P. Scipione, Massimo Politano, G. Rubino, C. Reina, N. Peccerillo, Leonardo Paloscia, A D‘Alleva, R Petacchi, M Pignalosa, Donatella Lucchetti, Fabrice Di Palma, R A La Mastra, M De Filippis, Benedetta Fontanella, Graziela Maria Zaniní, Giancarlo Casolo, Jacopo Del Meglio, Vito Maurizio Parato, E Genovesi, A D'Alimonte, A Miglioranza, N Alessandri, F. Moscariello, Ciro Mauro, Ariane Morassi Sasso, Pio Caso, Claudio Petrillo, Chiara Napoletano, S Paparoni, Vagner Gonçalves Bernardo, Raffaele Rotunno, Igino Oppo, Angelo Aloisio, A. Aurelio, Giovanni Licciardello, Leonarda Cassaniti, Giuseppina Maura Francese, Claudio Marcassa, Rosanna Villani, Federica Zorzoli, Federica Mileto, M. De Vecchis, D Scolozzi, Gabriele Lupi, Diego Caruso, E Rebulla, B La Fata, Maurizio Anselmi, Paolo Girardi, E Borruso, Giacomo Ferrantelli, Biagio Sassone, S Bressan, Michele Capriolo, Elisa Pelissero, M Piancastelli, M Gobbi, F Cocco, Maria Giuseppina Bruno, Sérgio Berti, Giuseppa Lo Surdo, Pietro Tanzi, Roberta De Rosa, E. Vilei, M R De Iaco, G Grassi, C. Zanella, Letizia Marullo, Gaetano Alfano, P Pelaggi, Robert Talarico, B Tuccillo, L Irace, Fabrizio Proietti, G. Di Croce, Luigi Di Lorenzo, A. Zarrilli, Marco Bongini, A. Ranise, Alessandro Aprile, Cristina Fornengo, V Capogrosso, A Tranghese, Bruno Golia, A Marziano, Loris Roncon, Claudio Picariello, Ermentina Bagni, Enri Leci, G. De Gregorio, Federico Gatto, Fiorella Piemonte, Carmine F. Gervasio, E Guerri, Ernest Belmonte, Francesco Marino, Natale Di Belardino, M. Nuzzo, M Epifani, G Comolatti, Barbara Conconi, D Benea, Gavino Casu, P. Merella, Mario Ammirati, Vincenzo Corrado, Daniele Spagnolo, S Caico, Sara Bonizzato, Massimo Margheri, Luigi Corrado, Roberto Antonicelli, C. Ferrigno, Amy Merlino, Daniele Nassiacos, Amedeo Antonelli, Alfredo Marchese, Mariagrazia Uguccioni, Anthony Villella, S Bechi, Francesco Bianco, Francesco Bedogni, Luca Dal Negro, L Donato, D Statile, Matthieu Cassin, Francesco Fedele, Antonino Granatelli, Simone Calcagno, Alessandro Politi, A Pani
Bibliographic record
VenueNutrition Metabolism and Cardiovascular Diseases · 2023
Typearticle
Languageen
FieldMedicine
TopicLipoproteins and Cardiovascular Health
Canadian institutionsHealth Care Foundation
FundersMenarini Group
KeywordsHypertriglyceridemiaMedicineHazard ratioInternal medicineStatinCohortConfidence intervalProportional hazards modelCohort studyTriglycerideCholesterol
Abstract
No abstract in any covered source. Its absence is recorded, not treated as a negative.
No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.090
Threshold uncertainty score0.654
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
Opus teacher head0.006
GPT teacher head0.210
Teacher spread0.204 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".
Quick stats
Citations2
Published2023
Admission routes1
Has abstractno