Dynamic hyperinflation in patients with severe asthma compared to healthy adults
Bibliographic record
Abstract
<p>Despite current medical management, exertional breathlessness is commonly experienced by adults with severe asthma limiting their exercise tolerance. A <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/cardiopulmonary-exercise-test" target="_blank">cardiopulmonary exercise test</a> may help identify the reasons for these symptoms to guide appropriate management and evaluate new interventions. For instance, exhalation can be interrupted by the next inspiration resulting in an increased end <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/expiratory-reserve-volume" target="_blank">expiratory lung volume</a>. Increasing end expiratory lung volume as ventilation increases is defined as dynamic hyperinflation.<a href="https://www.sciencedirect.com/science/article/pii/S2531043723001319?via=ihub#bib0001" target="_blank">1</a> Although there are reports of dynamic hyperinflation in asthma,<a href="https://www.sciencedirect.com/science/article/pii/S2531043723001319?via=ihub#bib0002" target="_blank">2</a>, <a href="https://www.sciencedirect.com/science/article/pii/S2531043723001319?via=ihub#bib0003" target="_blank">3</a>, <a href="https://www.sciencedirect.com/science/article/pii/S2531043723001319?via=ihub#bib0004" target="_blank">4</a> the frequency, severity and impact by exercise platform is unknown. </p>
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".