Relationships between Serum Interleukin-6, Radiographic Severity a WOMAC Index in Patients with Primary Knee Osteoarthritis
Bibliographic record
Abstract
Background: Osteoarthritis (OA) is the highest prevalent degenerative joint condition, leading to joint discomfort and impaired function. Objective: This study aimed to examin the relationship among serum interleukin-6 (IL-6) and knee osteoarthritis (KOA) signs as well as the relationship among serum IL-6 and radiographic severity in cases with primary KOA. Methods: This case-control research involved 50 primary KOA cases and 50 controls. Signs were measured through the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Results: Serum IL-6 was significantly elevated in OA cases than controls. WOMAC in OA cases ranged from 0 to 95 and Kellegren-Lawrence (KL) score mean was 2.7 ± 0.76.Serum IL-6 was significantly correlated with pain, physical function score, and radiographic score.Regression analysis revealed that IL-6 had a higher influence on WOMAC and KL score. Conclusion: Serum IL-6 is elevated in KOA cases. In addition, serum IL-6 is associated with OA signs and radiographic severity.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".