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Systemic Anticancer Therapy and Thromboembolic Outcomes in Hospitalized Patients With Cancer and COVID-19
Shuchi Gulati, Chih–Yuan Hsu, Surbhi Shah, Pankil Shah, Rebecca L. Zon, Susan Alsamarai, Joy Awosika, Ziad El-Bakouny, Babar Bashir, Alicia Beeghly, Stephanie Berg, Daniel De‐la‐Rosa‐Martinez, Deborah B. Doroshow, Pamela Egan, Joshua Fein, Daniel Flora, Christopher R. Friese, Ariel Fromowitz, Elizabeth A. Griffiths, Clara Hwang, Chinmay Jani, Monika Joshi, Hina Khan, Elizabeth J. Klein, Natalie Knox Heater, Vadim S. Koshkin, Daniel H. Kwon, Chris Labaki, Tahir Latif, Rana R. McKay, Gayathri Nagaraj, Elizabeth S. Nakasone, Taylor K. Nonato, Hyma Polimera, Matthew Puc, Pedram Razavi, Erika Ruíz‐García, Renée Maria Saliby, Aditi Shastri, Sunny Singh, Vicky Tagalakis, Diana Vilar‐Compte, Lisa B. Weissmann, Cy R. Wilkins, Trisha M. Wise‐Draper, Michael Wotman, James J. Yoon, Sanjay Mishra, Petros Grivas, Yu Shyr, Jeremy L. Warner, Jean M. Connors, Dimpy P. Shah, Rachel Rosovsky, Rikin Gandhi, Benjamin A. Gartrell, Sanjay Goel, Balázs Halmos, Della Makower, Darciann O' Sullivan, Nitin Ohri, R. Alejandro Sica, Amit Verma, Omar H. Butt, Mark A. Fiala, Jeffrey P. Henderson, Ryan Monahan, Keith Stockerl‐Goldstein, Alice Y. Zhou, Jacob D. Bitran, Sigrun Hallmeyer, Daniel Mundt, Sasirekha Pandravada, Philip V. Papaioannou, Mauli Patel, Mitrianna Streckfuss, Eyob Tadesse, Michael A. Thompson, Philip E. Lammers, Jonathan M. Loree, Irene Yu, Poorva Bindal, Barbara C.C. Lam, Mary Linton B. Peters, Andrew J. Piper‐Vallillo, Panos Arvanitis, Dimitrios Farmakiotis, Adam J. Olszewski, Kendra Vieira, Anne H. Angevine, Michael Bär, Salvatore A. Del Prete, Maryann Z. Fiebach, Anthony P. Gulati, Edward H. Hatton, Kaly Houston, Suzanne J. Rose, K. M. Steve Lo, Jamie Stratton, Paul L. Weinstein, Jorge A. García, Bertrand Routy, Irma Hoyo-Ulloa, Shilpa Gupta, Amanda Nizam, Nathan A. Pennell, Nima Sharifi, Claire Hoppenot, Ang Li, Danielle S. Bitterman, Toni K. Choueiri, George D. Demetri, Talal El Zarif, Narjust Florez, Dory Freeman, Antonio Giordano, Alicia K. Morgans, Anju Nohria, Sara M. Tolaney, Eliezer M. Van Allen, Wenxin Xu, Susan Halabi, Tian Zhang, Hannah Dzimitrowicz, John Leighton, Jerome Graber, Jessica E. Hawley, Elizabeth T. Loggers, Gary H. Lyman, Ryan C. Lynch, Andrew J. Portuguese, Michael T. Schweizer, Christopher Su, Lisa Tachiki, Shaveta Vinayak, Michael J. Wagner, Albert C. Yeh, Yvonne Dansoa, Na Tosha Gatson, Mina S. Makary, Jesse J. Manikowski, Joseph Vadakara, Kristena Yossef, Jennifer Beckerman, Sharad Goyal, Ian Messing, Destie Provenzano, Yuan James Rao, Lori J. Rosenstein, Dawn R. Steffes, Jessica Clément, Jonathan A. Cosin, Ahmad Daher, Mark E. Dailey, Rawad Elias, Omar Eton, Wylie Hosmer, Emily Hsu, Asha Jayaraj, Jeff Mather, Alvaro G. Menendez, Rajani Nadkarni, Oscar K. Serrano, Peter Paul Yu, Shirish M. Gadgeel, Sheela Tejwani, Melissa Accordino, Divaya Bhutani, Brianne E Bodin, Dawn L. Hershman, Matthew Ingham, Shaheer Khan, Cynthia Masson, Gary K. Schwartz, Mariam Alexander, Sara Matar, Daniel Y. Reuben, Eric Bernicker, John F. Deeken, Kelly J. Jeffords, Danielle Shafer, Ana I. Cárdenas‐Delgado, Rogelio Cuervo Campos, Ana Ramirez, Nadia Melissa Valdez-Reyes, David Gill, Mark A. Lewis, Clarke A. Low, Terence D. Rhodes, Michelle Jones, Abdul-Hai Mansoor, Sandeep H. Mashru, Mica A. Werner, Aaron Cohen, Brandon Hayes‐Lattin, Shannon K. McWeeney, Eneida R. Nemecek, Staci Williamson, Grant C. Lewis, Stephanie J. Smith, Mojtaba Akhtari, Dan R. Castillo, Kimberly Cortez, Kyu Park, Mark E. Reeves, Timothy E. O’Connor, Jessica K. Altman, Michael Gurley, Mary F. Mulcahy, Firas Wehbe, Eric B. Durbin, Amit Kulkarni, Heather H. Nelson, Vidhyalakshmi Ramesh, Zohar Sachs, Grace L. Wilson, Aditya Bardia, Genevieve M. Boland, Justin F. Gainor, Jeffrey Peppercorn, Kerry L. Reynolds, Leyre Zubiri, Jian Campian, Katherine E. Smith, Tanios Bekaii‐Saab, Aakash Desai, Þorvarður R. Hálfdánarson, Michael J. Joyner, Irbaz B Riaz, Jonathon W. Senefeld, Colt Williams, Mark Bonnen, Daruka Mahadevan, Amelie G. Ramírez, Mary Salazar, Chen‐Pin Wang, Ruben A. Mesa, Nathaniel Bouganim, Arielle Elkrief, Feras Moria, Justin Panasci, Jesse Papenburg, Donald C. Vinh, Rahul Nanchal, Harpreet Singh, Nadia Bahadur, Ting Bao, Puja H. Nambiar, Roisin E. O’Cearbhaill, Esperanza B. Papadopoulos, John Philip, Gregory J. Riely, Mark E. Robson, Adam J. Schoenfeld, Rulla M. Tamimi, Kim Cerrone, Jennifer A. Dill, Bryan A. Faller, Archana Ajmera, Sharon S. Brouha, Sharon Choi, Albert Hsiao, Erin Reid, Padmanabh Bhatt, Melissa G. Mariano, Carey C. Thomson, Mary Grace Glace, Jeanna Knoble, Cameron Rink, Rosemary Zacks, Sibel Blau, CarrieAnn Brown, Swathi Namburi, Lauren Pomerantz, Marc A. Rovito, Pragati E. Advani, Tara Cronin, Bridget Fleissner, Shipra Goel, Dharmesh Gopalakrishnan, Francisco J. 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Venepalli, Praveen Vikas, Yousef Zakharia, Anne Boldt, Leslie A. Fecher, Chris Su, Ragneel R. Bijjula, Blanche H. Mavromatis, Mildred E. Seletyn, Barbara R. Wood, Qamar U. Zaman, Virginia Kaklamani, Alaina J. Brown, Lawrence J. Charles, Alex Cheng, Marta A. Crispens, Sarah Croessmann, Elizabeth J. Davis, Tan Ding, Stephany N. Duda, Kyle T. Enriquez, Benjamin French, Erin A. Gillaspie, Daniel Hausrath, Cassandra Hennessy, Douglas B. Johnson, Judy T. Lewis, Xuanyi Li, Lauren S. Prescott, Sonya Reid, Sara Saif, David Slosky, Carmen C. Solórzano, Tianyi Sun, Lucy Lu Wang, Yuanchu James Yang, David M. Aboulafia, Theresa M. Carducci, Karen J. Goldsmith, Susan Van Loon, Ümit Topaloĝlu, Joan K. Moore, Wilhelmina D. Cabalona, Elizabeth Shisler, Briana Barrow McCollough, Prakash Peddi, L Rosen, Mehmet Asım Bilen, Cecilia A. Castellano, Deepak Ravindranathan, Navid Hafez, Roy S. Herbst, Patricia LoRusso, Maryam B. Lustberg, Tyler Masters, Catherine Stratton, Corrie Painter, Solange Peters
Bibliographic record
VenueJAMA Oncology · 2023
Typearticle
Languageen
FieldMedicine
TopicCOVID-19 and healthcare impacts
Canadian institutionsJewish General Hospital
FundersNational Center for Advancing Translational SciencesNational Institute of Allergy and Infectious DiseasesNational Cancer InstituteNational Institute on Aging
KeywordsMedicineInternal medicineCancerRetrospective cohort studyIntensive care unitIncidence (geometry)Cancer registryLung cancer
Abstract
OpenAlex records an abstract for this work, but it could not be fetched just now.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.024
Threshold uncertainty score0.723
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
Opus teacher head0.064
GPT teacher head0.425
Teacher spread0.361 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".
Quick stats
Citations9
Published2023
Admission routes1
Has abstractyes