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Record W4385931661 · doi:10.21203/rs.3.rs-3220017/v1

Unveiling Tissue Marker Migration in MRI-Guided Vacuum-Assisted Biopsies: Frequency, Factors, and Implications

2023· preprint· en· W4385931661 on OpenAlexaff
Orit Golan, Sapir Lazar, Tehillah S. Menes, Vivianne Freitas, Rivka Kessner, Tamar Shalmon, Rina Neeman, Diego Mercer, Yoav Amitai

Bibliographic record

VenueResearch Square · 2023
Typepreprint
Languageen
FieldMedicine
TopicMRI in cancer diagnosis
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsPathologyNuclear magnetic resonanceMedicinePhysics

Abstract

fetched live from OpenAlex

Abstract Purpose To evaluate the frequency and factors associated with clip migration in MRI-guided breast biopsies. Methods and materials We retrospectively evaluated all MRI-guided biopsies performed between January 2013 and December 2020 in our institution for clip migration. Only patients with follow-up breast MRI showing the clip were included in the study. Migration was defined as > 1 cm movement from the target lesion. Migration frequency and directions were recorded. Different factors associated with clip migration were analyzed using statistical tests as appropriate. Results A total of 291 biopsies in 268 women were included in the study with 31 migration events recorded (11%, 95%CI 7–15). All migrations occurred along the biopsy tract, 30 of them distal from the tip of the needle (97%). More than 50% regional fat (around the target lesion) was the strongest factor associated with migration, seen in 21/140 (15%), compared to 10/150 (7%) with less than 50% local fat (P = 0.023). Global fatty breast was more loosely associated with migration, showing borderline significance (P = 0.06). Other factors did not correlate with clip migration, including lesion size, depth or location, pathology result, breast thickness or biopsy approach. Conclusion Although clip migration following breast MRI-guided biopsy is an uncommon event, it occurs more often when the target lesion is surrounded by fat, with the clip usually displaced away from the biopsy needle. This information could be valuable for pre-surgical localization and surgical planning.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.016
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.012

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.016
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0020.002
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.207
GPT teacher head0.477
Teacher spread0.269 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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