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Record W4385953304 · doi:10.1177/17151635231191491

Maximizing secondary prevention for patients with ASCVD: Where does colchicine fit in cardiovascular disease prevention?

2023· article· en· W4385953304 on OpenAlexaffvenue
William Semchuk, Claudia Bucci

Bibliographic record

VenueCanadian Pharmacists Journal / Revue des Pharmaciens du Canada · 2023
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicInflammasome and immune disorders
Canadian institutionsSaskatchewan HealthSaskatchewan Health AuthorityHealth Sciences CentreSunnybrook Health Science Centre
Fundersnot available
KeywordsMedicineInternal medicineColchicineSecondary preventionAtherosclerotic cardiovascular diseaseCardiologyDiseaseOncology

Abstract

fetched live from OpenAlex

CaseMr. TH is a 48-year-old man who had a myocardial infarction at home.His wife found him unresponsive and called 911, who supported her in the provision of cardiopulmonary resuscitation until emergency medical services arrived, at which point he was resuscitated and transported to hospital.At hospital, he went directly to the cardiac catheterization lab, where diffuse disease was noted and a single stent implanted.Through his hospitalization, he was initiated on a beta-blocker, an angiotensin-converting enzyme (ACE) inhibitor, a statin, acetyl salicylic acid (ASA) and ticagrelor.His blood pressure is 125/80 mmHg, low-density lipoprotein (LDL) is 1.8 mmol/L and he has normal left ventricular function.He was discharged home in stable condition.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.008
Threshold uncertainty score0.017

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0020.001
Scholarly communication0.0020.002
Open science0.0010.001
Research integrity0.0040.004
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.249
Teacher spread0.235 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes2
Has abstractyes

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