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Preface

2019· book-chapter· ca· W4385974660 on OpenAlexaboutno aff

Bibliographic record

Venuenot available
Typebook-chapter
Languageca
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetics, Bioinformatics, and Biomedical Research
Canadian institutionsnot available
Fundersnot available
KeywordsPopulationEvolutionary biologyGenealogyBiologyPopulation geneticsGeneticsHistorySociologyDemography

Abstract

fetched live from OpenAlex

Extract My mind’s-eye title for this book is A Fireside Chat about Molecular Population Genetics. Winters are cold here in Canada, and I like to sit back by a fire and warm up to the alluring collection of ideas in molecular population genetics. I’d like you to, as well. If you live somewhere hot, then substitute the fireplace and cushions with a shady tree and hammock. Let this book be your hot chocolate or your lemonade. That sums up my outlook for this Primer. So, what are these alluring ideas? Here are a few savory questions that molecular population genetics aims to answer. What are the genomic inner-workings of adaptations and how do we see them in DNA? How much of evolution is actually driven by natural selection versus something else? How does the ebb and flow in the abundance of individuals over time get marked onto chromosomes to record this history? Molecular population genetics is the main way that researchers apply theory to data to answer questions like these. It provides the way to learn about how evolution works and how it shapes species by looking at DNA. It lets us understand the logic of how mutations originate to then change in abundance in populations to potentially get locked-in as DNA sequence divergence between species. This crucial role in modern science stems in no small part from the mainstreaming of population genomic sequencing technologies that reinforce the ever-growing relevance of molecular population genetics to diverse problems in biology. All of this makes it important for you to start on your way to learning about molecular population genetics.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.638
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.0040.008

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.274
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes1
Has abstractyes

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