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General principles and classification of soft tissue sarcomas

2023· article· en· W4385978297 on OpenAlexaff
Ahmet Salduz, Serkan Bayram

Bibliographic record

VenueTürk Ortopedi ve Travmatoloji Birliği Derneği · 2023
Typearticle
Languageen
FieldMedicine
TopicSarcoma Diagnosis and Treatment
Canadian institutionsStantec (Canada)
Fundersnot available
KeywordsSoft tissueComputer scienceMedicinePathology

Abstract

fetched live from OpenAlex

Sarkom; kemik, kıkırdak, yağ, kas, kan damarları, fibröz doku veya diğer bağ ya da destekleyici doku dâhil olmak üzere vücudun tüm mezankimal kökenli dokularından kaynaklanan malign tümörlerin genel adıdır.Amerikan Kanser Derneği, 2023 yılı için Amerika Birleşik Devletleri'nde yaklaşık 13.400 (erkeklerde 7.400 ve kadınlarda 6.000) yeni yumuşak doku sarkomu teşhis edileceğini ve yaklaşık 5.140 kişinin (2.720 erkek ve 2.420 kadın) yumuşak doku sarkomundan öleceğini tahmin etmektedir.Sarkom gelişimiyle bağlantılı bazı genetik tanılar ve çevresel faktörler bildirilmesine rağmen sarkomların çoğu sporadik ve idiopatiktir.Yumuşak doku ve kemik tümörleri sınıflandırması (cilt 3) beşinci baskısı Dünya Sağlık Örgütü (DSÖ) tarafından 2020 yılında yayımlandı.Son sınıflama ile 100'den fazla farklı histolojik ve moleküler alt tipte yumuşak doku sarkomu olduğu ve her bir alt tipin değişken klinik davranış sergilediği bildirilmiştir.Yumuşak doku tümörü sınıflandırması genel olarak hücre türüne göre yapılır.Bunun için morfolojik, immünohistokimyasal ve genetik özelliklere bakılır.Tümör bölgesi ve derecesinin yanı sıra, yumuşak doku sarkomunun histolojik alt tipi önemli bir prognostik göstergedir.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.008
Threshold uncertainty score0.025

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.003
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0080.004
Science and technology studies0.0010.003
Scholarly communication0.0020.002
Open science0.0020.001
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0080.008

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.059
GPT teacher head0.317
Teacher spread0.259 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2023
Admission routes1
Has abstractyes

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