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Record W4385978523 · doi:10.5772/intechopen.1002328

Ocular Manifestations of Sarcoidosis

2023· book-chapter· en· W4385978523 on OpenAlexaff
Abhishek Sethi, Corrina P. Azarcon, Monique Munro

Bibliographic record

VenueIntechOpen eBooks · 2023
Typebook-chapter
Languageen
FieldMedicine
TopicSarcoidosis and Beryllium Toxicity Research
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsSarcoidosisMedicineEpiscleritisUveitisScleritisSystemic diseaseDermatologyGlaucomaEyelidPathologyBiopsyDiseaseOphthalmology

Abstract

fetched live from OpenAlex

Sarcoidosis is a complex granulomatous systemic inflammatory disease that can affect the eye and its adnexa. Ocular sarcoidosis is a leading cause of inflammatory eye disease that can result in significant visual impairment. Ocular inflammation can manifest with a wide range of clinical presentations and can involve almost any structure within or around the orbit causing uveitis, episcleritis/scleritis, eyelid anomalies, conjunctival granulomas, optic neuropathy, lacrimal gland enlargement, glaucoma, and/or cataract. The diagnosis of ocular sarcoidosis is typically established based on the presence of characteristic ophthalmologic findings, along with a positive tissue biopsy or bilateral hilar adenopathy on chest imaging. Topical, periocular, and systemic corticosteroids are commonly used to treat ocular sarcoidosis. Chronic cases or refractory cases may warrant immunomodulator therapy. Visual prognosis is contingent on severity of inflammation, time to treatment, and secondary ocular complications. This chapter will discuss the presentation, diagnosis, treatment, and prognosis of patients with ocular sarcoidosis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.738
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.083
GPT teacher head0.332
Teacher spread0.248 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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