MétaCan
Menu
← Back to cohort
Record W4386006081 · doi:10.1002/9781118441213.rtd0052

Lupus Erythematosus

2016· other· en· W4386006081 on OpenAlexaff
Mark Goodfield, Jan Dutz, Collette McCourt

Bibliographic record

Venuenot available
Typeother
Languageen
FieldMedicine
TopicSystemic Lupus Erythematosus Research
Canadian institutionsVancouver General Hospital
Fundersnot available
KeywordsDermatomyositisMedicineRheumatoid arthritisConnective tissue diseasePathologicalAutoimmunitySystemic lupus erythematosusConnective tissueLupus erythematosusDiseaseOrgan systemSystemic diseaseAutoimmune diseasePathologyImmunologyMixed connective tissue diseaseDermatologyAntibody

Abstract

fetched live from OpenAlex

Abstract Lupus erythematosus (LE) is a complex spectrum of disease, involving one or multiple organ systems, and characterized by humoral and cellular autoimmunity, resulting in combinations of skin, joint, vascular and internal organ involvement. Skin disease occurs in the overwhelming majority of patients, and the patterns of skin involvement form an important part of subclassification, with localized discoid lupus usually being a single‐system manifestation, and acute cutaneous LE part of a potentially fatal multisystem disease. Intermediate forms, including subacute cutaneous LE are common and variable in their involvement of other organ systems. Ultraviolet exposure is an important disease precipitant. LE forms a major part of the group of disorders called connective tissue diseases, along with systemic sclerosis, localized and generalized morphoea, dermatomyositis, rheumatoid arthritis and Sjögren syndrome on the basis of clinical, pathological and immunological overlap.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.049
Threshold uncertainty score0.164

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0490.015

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.316
Teacher spread0.294 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2016
Admission routes1
Has abstractyes

Explore more

Same topicSystemic Lupus Erythematosus Research→French-language works237,207→