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Record W4386033344 · doi:10.21203/rs.3.rs-3249906/v1

Flower Species Ingredient Verification Using Orthogonal Molecular Methods

2023· preprint· en· W4386033344 on OpenAlexaff
Subramanyam Ragupathy, A Thirugnanasambandam, Thomas Henry, Vinayagam Varathan, Sneha Ragupathy, Steven G. Newmaster

Bibliographic record

VenueResearch Square · 2023
Typepreprint
Languageen
FieldMedicine
TopicPhytochemicals and Antioxidant Activities
Canadian institutionsUniversity of Guelph
Fundersnot available
KeywordsIngredientActive ingredientCosmeticsHealth benefitsPhytochemicalFingerprint (computing)BiotechnologyBiochemical engineeringFood scienceBiologyTraditional medicineChemistryComputer scienceBotanyMedicineArtificial intelligenceOrganic chemistryPharmacology

Abstract

fetched live from OpenAlex

Abstract Flowers are gaining considerable interest by consumers as ingredients in food, beverages, cosmetics, and natural health products. The supply chain trades in multiple forms of botanicals including fresh whole flowers, which are easier to identify than dried flowers or flowers processed as powdered or liquid extracts. There is a gap in the scientific methods available for the verification of flower species ingredients traded in the supply chain of multiple markets. The objective of this paper is to develop methods for flower species ingredient verification using two orthogonal methods. More specifically the objectives of this study employed both 1) DNA based molecular diagnostic methods, and 2) NMR metabolite fingerprint methods in the identification of 23 common flower species ingredients. NMR data analysis reveals considerable information on the variation of metabolites present in different flower species including color variants within species. This study provides a comparison of the benefits and limitations of alternative methods for flower species ingredient supply chain verification needed to support quality assurance. The metabolomic approach provides a basis for understanding the phytochemical structure of natural products that may be eventually linked to efficacy in clinical trials and label claims with respect to health benefits of specific botanical formulations.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.002
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.004
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.303
GPT teacher head0.529
Teacher spread0.226 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2023
Admission routes1
Has abstractyes

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