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Record W4386281413 · doi:10.29261/pakvetj/2023.049

Molecular Characterization of Hydatigera taeniaeformis Recovered from Rats: An Update from Pakistan

2023· article· en· W4386281413 on OpenAlexaboutno aff
Mughees Aizaz Alvi, Ayed Alshammari, Rana Muhammad, Athar Ali, Imaad Rashid, Muhammad Saqib, Warda Qamar, Muhammad Shafeeq, Hussam Askar, Naser Abdelsater, Li Li, Khurram Ashfaq, Asif Ali Butt, Bao‐Quan Fu, Hongbin Yan, Wan‐Zhong Jia

Bibliographic record

VenuePakistan Veterinary Journal · 2023
Typearticle
Languageen
FieldMedicine
TopicParasitic infections in humans and animals
Canadian institutionsnot available
FundersNational Key Research and Development Program of China
KeywordsVeterinary medicineMedicine

Abstract

fetched live from OpenAlex

Rodents are one of the most abundant and successful mammals on the planet.The rats harbor the metacestode stage of Hydatigera taeniaeformis serving as the intermediate hosts, whereas cats act as definitive hosts of the parasite.The incidence of the larval stage in rats has been documented in various regions of the world.To best of our knowledge, the mainstream studies on the genetic diversity of H. taeniaeformis are based on the cox1 gene which precludes an in-depth analysis of genetic variation in the parasite.To provide insights about nad1 gene-based genetic variation, in continuation of our previous work, we thereby in this study report H. taeniaeformis infection in the urban murine population from the Faisalabad district of Pakistan and presented genetic polymorphism using the nad1 gene.Out of 38 isolates investigated in the study, a total of 13 haplotypes were found with high haplotype diversity (Hd = 0.909), while the nucleotide diversity was found to be 0.02340 in the study population.The neutrality study found a significant level of nucleotide polymorphism, indicating a rise in low-frequency polymorphism, which might be attributed to global population growth of the parasite.Construction of phylogenetic comprising isolates from Kazakhstan, Finland, Turkiye, Canada, Germany, France, and China revealed that Pakistani isolates of H. taeniaeformis are distinct and formed a separate cluster.Further research utilising full-length multiple mitochondrial genes is required to understand the molecular epidemiology of H. taeniaeformis on the global scale.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.700
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.035
GPT teacher head0.349
Teacher spread0.314 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2023
Admission routes1
Has abstractyes

Explore more

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