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Record W4386316864 · doi:10.1002/9781119862611.ch8

The Immune System

2023· other· en· W4386316864 on OpenAlexaff
Robin Saar, Sarah Dodd

Bibliographic record

Venuenot available
Typeother
Languageen
FieldMedicine
TopicDermatology and Skin Diseases
Canadian institutionsUniversity of Guelph
Fundersnot available
KeywordsImmune systemInnate immune systemImmunologyImmunityAcquired immune systemBiologyInflammationInnate lymphoid cell

Abstract

fetched live from OpenAlex

The immune system fights foreign substances (infectious agents that are perceived to cause harm to the host) that may be found on the skin, in body tissues, the gastrointestinal tract, and in body fluids such as blood. The immune system consists of innate and adaptive systems. While these two systems function in different ways, they both work to protect the host from foreign substances that may detrimentally alter the health of the host (InformedHealth.org [Internet]. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG) 2006-. The innate and adaptive immune systems. [Updated 2020 Jul 30]). A large part of the immune system's controlling function is focused on regulating the relationship between the host and the microbiota. To aid in this function, the highest number of immune cells reside where foreign substances would be absorbed by the host, the skin, and the GI tract (Belkaid, Y., Hand, T.W. (2014). Role of the microbiota in immunity and inflammation. Cell 157 (1): 121–141. 10.1016/j.cell.2014.03.011). When there is a failure in controlling the dialogue that would prevent or misdirect an immune response, pathologies such as allergies, autoimmune, and inflammatory disorders occur (Belkaid, Y., Hand, T.W. (2014). Role of the microbiota in immunity and inflammation. Cell 157 (1): 121–141. 10.1016/j.cell.2014.03.011).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.068
Threshold uncertainty score0.228

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.002
Scholarly communication0.0050.002
Open science0.0010.004
Research integrity0.0030.003
Insufficient payload (model declined to judge)0.0680.032

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.260
Teacher spread0.251 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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