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Technology & Inventions

2023· article· en· W4386371569 on OpenAlexaboutno aff
Madeline Talbot

Bibliographic record

VenueEmergency Medicine News · 2023
Typearticle
Languageen
FieldMedicine
TopicCardiac Arrest and Resuscitation
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineExtracorporeal membrane oxygenationLife supportExtracorporealBlood oxygenationAnesthesiaIntensive care medicineSurgery

Abstract

fetched live from OpenAlex

Life Support Device Receives FDA Approval Abbott has received two clearances from the Food & Drug Administration for its CentriMag life support system. The system's blood pump had previously been approved for use up to six hours, but this has been expanded to allow for longer usage by physicians who are assessing patients who require extracorporeal membrane oxygenation (ECMO). The device provides physicians time for critical care decision-making for patients whose hearts are not able to pump enough blood on their own, according to a company press release. (Abbott. April 25,2023; https://bit.ly/3pmcNmj.) The life support device has been used to treat patients who have had open heart surgery and COVID-19 and for those who require ECMO support. Abbott also received clearance for a multisystem life support pack that includes the blood pump and an oxygenator intended for short-term cardiopulmonary support. The preconnected pack reduces the number of steps taken by physicians when providing critical care. Find more information about the CentriMag system at www.abbott.com.Figure: life support system, Abbott, CentriMag, blood pump, extracorporeal membrane oxygenation, ECMO, COVID-19, cardiopulmonary support, pain management, migraine, Nerivio, Theranica, remote electrical modulation, REN, nervous system, nanotechnology, respiratory infection, PCR, QolorEx, influenzaPain Management for Migraine The FDA has granted clearance to the Nerivio wearable for acute and preventive treatment of migraines. Theranica's neuromodulation device is a physician-prescribed, drug-free alternative to traditional migraine treatments that users wrap around the upper arm, where the device activates internal pain management by dispensing remote electrical modulation (REN) to the nervous system. A total of 248 participants were instructed to use either REN with the Nerivio wearable or a placebo every other day for eight weeks as part of a double-blind, randomized, placebo-controlled clinical trial. Participants using Nerivio experienced four fewer migraine days per month from baseline compared with the placebo group, who experienced 1.3 fewer migraine days per month, reported the company. (PRNewswire. Feb. 28, 2023; https://bit.ly/3XvVZ8O.) The treatment lasts 45 minutes. The drug-free device is an alternative pain management system for migraines that has no adverse effects, making the device a viable option for adolescents and pregnant individuals, who are reluctant to take medication due to concerns about effects on the fetus, a Medscape article reported. (June 23, 2023; https://bit.ly/3CVw3dr.) Visit www.theranica.com for more information. Diagnostic Nanotechnology for Respiratory Infection A startup from McGill University, Beeta Biomed, Inc., has developed a prototype diagnostic and molecular PCR test called QolorEX for detecting respiratory infections such as influenza A and B and COVID-19. The test device uses colorimetric detection of RNA to identify viruses from a saliva sample and injects light-excited hot electrons from the surface of a nanoplasmonic sensor to increase the speed of the test, reported Medscape. (June 20, 2023; https://bit.ly/3XzVr1Z.) The user inserts the cartridge with the saliva sample into an imaging system that then delivers results automatically to a computer or smart device within 15 minutes without the need to ship samples to a lab for testing. The system does not require users to mix reagents manually, reducing the risk of user error that could yield false results. The device can detect different variants of H1N1 influenza and SARS-CoV-2. The device detected positive COVID-19 cases with 99% specificity in a preclinical test of 33 participants, according to a company release. (McGill. April 18, 2023; https://bit.ly/435gFWu.) The developmental team said it anticipates partnering with a manufacturing company to make the test commercially available, and said they see the potential for it to detect bacterial infections and even cancer in the future. Visit www.mcgill.ca for more information. MS. TALBOT is an editorial assistant for Emergency Medicine News. Share this article on Twitter and Facebook. Access the links in EMN by reading this on our website: www.EM-News.com. Comments? Write to us at [email protected].

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.086
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.054
GPT teacher head0.370
Teacher spread0.316 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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