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Record W4386465681 · doi:10.1093/jcag/gwad009

The 2023 Impact of Inflammatory Bowel Disease in Canada: Indirect (Individual and Societal) and Direct Out-of-Pocket Costs

2023· review· en· W4386465681 on OpenAlexafffundabout
M Ellen Kuenzig, James Im, Stephanie Coward, Joseph W. Windsor, Gilaad G. Kaplan, Sanjay K. Murthy, Eric I. Benchimol, Çharles N. Bernstein, Alain Bitton, Jennifer Jones, Kate Lee, Juan Nicolás Peña-Sánchez, Noelle Rohatinsky, Sara Ghandeharian, Tyrel Jones May, Sahar Tabatabavakili, Rohit Jogendran, Jake Weinstein, Rabia Khan, Elias Hazan, Mira Browne, Tal Davis, Quinn Goddard, Julia Gorospe, Kate Latos, Kate Mason, Jack Kerr, Naji Balche, Anna Sklar, Laura E. Targownik

Bibliographic record

VenueJournal of the Canadian Association of Gastroenterology · 2023
Typereview
Languageen
FieldHealth Professions
TopicAdolescent and Pediatric Healthcare
Canadian institutionsUniversity of SaskatchewanInstitute for Clinical Evaluative SciencesUniversity of OttawaMcGill University Health CentreMemorial University of NewfoundlandCrohn's and Colitis CanadaPublic Health OntarioDalhousie UniversitySickKids FoundationUniversity of TorontoUniversity of ManitobaUniversity Health NetworkOttawa HospitalMount Sinai HospitalUniversity of Calgary
FundersJanssen CanadaJanssen BiotechTakeda CanadaFresenius KabiGoddard Space Flight CenterAbbVie CanadaSandoz CanadaCrohn's and Colitis CanadaFerringPfizer CanadaAmgen CanadaCanadian Association of GastroenterologyMylanEli Lilly and CompanyBristol-Myers SquibbShireTakeda FoundationGilead SciencesEli Lilly CanadaDairy Farmers of OntarioMerck CanadaUniversity of TorontoAbbVieMerckAmgenHospital for Sick ChildrenPfizerBristol-Myers Squibb CanadaRoche Canada
KeywordsPresenteeismAbsenteeismIndirect costsMedicineProductivitySick leaveEconomic costInflammatory bowel diseaseUnemploymentHealth careEnvironmental healthTotal costDiseaseBusinessEconomicsEconomic growthPhysical therapyInternal medicine

Abstract

fetched live from OpenAlex

People living with inflammatory bowel disease (IBD) and their caregivers are faced with indirect and out-of-pocket costs that they would not otherwise experience. These costs impact one's ability to contribute to the economy to their fullest potential. The indirect costs of IBD in Canada are estimated to be at least $1.51 billion in 2023 and include costs associated with lost productivity resulting from a combination of missed work (absenteeism), decreased workplace productivity (presenteeism), unemployment, premature mortality, and caregiving costs. Unemployment is the largest contributor to indirect costs ($1.14 billion), followed by costs of absenteeism and presenteeism ($285 million). Caregiving costs for children with IBD are estimated to be nearly $58 million. Canadians with IBD also pay $536 million every year for care that is not covered by universal or supplemental private health insurance; this includes allied healthcare (e.g., care provided by psychologists), medication, and other supportive therapy. Combined, the indirect and out-of-pocket costs of IBD in Canada are estimated at more than $2 billion CAD in 2023. This is substantially higher than the estimate of $1.29 billion in Crohn's and Colitis Canada's 2018 Impact of IBD report with differences attributable to a combination of rising prevalence, inflation, and the addition of presenteeism and caregiving costs to the total indirect costs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.426
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.055
GPT teacher head0.374
Teacher spread0.319 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations19
Published2023
Admission routes3
Has abstractyes

Explore more

Same venueJournal of the Canadian Association of GastroenterologySame topicAdolescent and Pediatric HealthcareFrench-language works237,207