Multi-object 3D segmentation of brain structures using a geometric deformable model with a priori knowledge
Bibliographic record
Abstract
Brain structure segmentation in 3D Magnetic Resonance Images is crucial for understanding neurodegenerative disorders. Manual segmentation is error-prone, necessitating robust automated techniques. In this paper, we introduce a novel and robust approach for the simultaneous segmentation of multiple brain structures in MRI images. Our method involves the concurrent evolution of 3D surfaces toward predefined anatomical targets, employing an efficient multi-object generalized fast marching method (MOGFMM) for simultaneous object detection. Additionally, we propose an effective evolution function that integrates prior knowledge from anatomical and probabilistic atlases, as well as spatial relationships among the segmented structures. Each deformable surface corresponds to a specific structure. To validate our approach, we conducted experiments on a dataset of real brain images (IBSR) and compared the results with several state-of-the-art methods. The obtained results were promising, demonstrating the effectiveness and superiority of our developed method.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.002 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.002 |
| Bibliometrics | 0.002 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.002 | 0.001 |
| Open science | 0.002 | 0.002 |
| Research integrity | 0.003 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".