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Record W4386707774 · doi:10.1038/s41586-023-06418-5

Early-childhood linear growth faltering in low- and middle-income countries

2023· article· en· W4386707774 on OpenAlexaff
Jade Benjamin‐Chung, Andrew Mertens, John M. Colford, Alan Hubbard, Mark J. van der Laan, Jeremy Coyle, Oleg Sofrygin, Weixin Cai, Anna Nguyen, Nolan N. Pokpongkiat, Stephanie Djajadi, Anmol Seth, Wendy Jilek, Esther Jung, Esther O. Chung, Sonali Rosete, Nima S. Hejazi, Ivana Malenica, Haodong Li, Ryan Hafen, Vishak Subramoney, Jonas Häggström, Thea Norman, Kenneth H. Brown, Parul Christian, Benjamin F. Arnold, Souheila Abbeddou, Linda S. Adair, Tahmeed Ahmed, Asad Ali, Hasmot Ali, Per Ashorn, Rajiv Bahl, Maurício L. Barreto, France Bégin, Pascal Bessong, Maharaj Kishan Bhan, Nita Bhandari, Santosh K. Bhargava, Zulfiqar A Bhutta, Robert E. Black, Ladaporn Bodhidatta, Delia B. Carba, Inés González-Casanova, William Checkley, Jean E. Crabtree, Kathryn G. Dewey, Christopher Duggan, Caroline Fall, Abu Syed Golam Faruque, Wafaie Fawzi, José Quirino da Silva Filho, Robert H. Gilman, Richard L. Guerrant, Rashidul Haque, Sonja Y. Hess, Eric R. Houpt, Jean H. Humphrey, Najeeha Talat Iqbal, Elizabeth Yakes Jimenez, Jacob John, Sushil Matthew John, Gagandeep Kang, Margaret Kosek, Michael S. Kramer, Alain Labrique, Sang Lee, Aldo Â. M. Lima, Mustafa Mahfuz, Tjale Cloupas Mahopo, Kenneth Maleta, Dharma Manandhar, Karim Manji, Reynaldo Martorell, Sarmila Mazumder, Estomih Mduma, Venkata Raghava Mohan, Sophie E. Moore, Ishita Mostafa, Robert Ntozini, Mzwakhe Emanuel Nyathi, Maribel Paredes Olórtegui, William A. Petri, Prasanna Samuel, Andrew M. Prentice, Najeeb Rahman, Harshpal Singh Sachdev, Kamran Sadiq, Rajiv Sarkar, Naomi Saville, Saijuddin Shaikh, Bhim P. Shrestha, Sanjaya K. Shrestha, Alberto M. Soares, Bakary Sonko, Aryeh D. Stein, Erling Svensen, Sana Syed, Fayaz Umrani, Honorine Ward, Keith P. West, Lee Wu, Seungmi Yang

Bibliographic record

VenueNature · 2023
Typearticle
Languageen
FieldNursing
TopicChild Nutrition and Water Access
Canadian institutionsMcGill UniversityMcGill University Health Centre
FundersNational Institute of Allergy and Infectious DiseasesNational Institute of Diabetes and Digestive and Kidney DiseasesNational Heart, Lung, and Blood InstituteMedical Research CouncilBill and Melinda Gates Foundation
KeywordsLinear growthLow and middle income countriesLow incomeEconomicsDemographic economicsDeveloping countryEconomic growthMathematics

Abstract

fetched live from OpenAlex

. Stunting, a form of linear growth faltering, increases the risk of illness, impaired cognitive development and mortality. Global stunting estimates rely on cross-sectional surveys, which cannot provide direct information about the timing of onset or persistence of growth faltering-a key consideration for defining critical windows to deliver preventive interventions. Here we completed a pooled analysis of longitudinal studies in low- and middle-income countries (n = 32 cohorts, 52,640 children, ages 0-24 months), allowing us to identify the typical age of onset of linear growth faltering and to investigate recurrent faltering in early life. The highest incidence of stunting onset occurred from birth to the age of 3 months, with substantially higher stunting at birth in South Asia. From 0 to 15 months, stunting reversal was rare; children who reversed their stunting status frequently relapsed, and relapse rates were substantially higher among children born stunted. Early onset and low reversal rates suggest that improving children's linear growth will require life course interventions for women of childbearing age and a greater emphasis on interventions for children under 6 months of age.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.011
Threshold uncertainty score0.483

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.254
Teacher spread0.246 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations113
Published2023
Admission routes1
Has abstractyes

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