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Record W4386809570 · doi:10.18280/ria.370411

Anomaly Detection in Human Disease: A Hybrid Approach Using GWO-SVM for Gene Selection

2023· article· en· W4386809570 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueRevue d intelligence artificielle · 2023
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMachine Learning in Bioinformatics
Canadian institutionsnot available
Fundersnot available
KeywordsSelection (genetic algorithm)Support vector machineAnomaly detectionGene selectionVector (molecular biology)GeneComputer scienceBiologyArtificial intelligenceComputational biologyPattern recognition (psychology)GeneticsGene expression

Abstract

fetched live from OpenAlex

The goal is to facilitate early disease detection.A Grey Wolf Optimizer (GWO) was implemented in the proposed method, a meta-heuristic algorithm known for its efficiency in reducing computational time for high-dimensional data.This optimization technique simplifies the problem by breaking it into manageable subsets.Following this, a filter approach, such as analysis of variance (ANOVA), was used to select informative genes from the reduced data.A Support Vector Machine (SVM) was also used as a classifier to select genes that efficiently categorize anomalous cases, serving as a fitness function-this combined approach, referred to as GWO-SVM, and aimed to reduce computational time while improving accuracy.The experimental results demonstrated that the proposed method achieved an accuracy rate of 96.46% in predicting disease detection, representing a significant improvement compared to previous methods.These findings underscore the potential of the GWO-SVM approach in advancing anomaly detection in human diseases.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.397
Threshold uncertainty score0.634

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.301
Teacher spread0.269 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it