3D‐Printed Low‐Cost Artificial Corneal Perfusion Chamber for Investigating Corneal Physiology and Diseases in Different Animal Species
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Corneal blindness is the fourth‐most common form of blindness in the world. The only current therapy is a cornea transplant; however, only 1 out of 70 people would receive a corneal transplant. While cell models can be used to develop therapies for corneal diseases, they cannot recapitulate the complexity of the tissue, as displayed in animal models, which are expensive and complex to carry out. Thus, ex vivo models that can recapitulate the cornea structure are critical. Herein, a series of open‐access 3D‐printed corneal perfusion chambers that can closely recapitulate the native curvature of the cornea is presented, while also maintaining internal ocular pressure, for different animal species. These devices are made available open access to the scientific community, allow the study of corneal physiology, diseases, and to aid in future therapeutic discovery for cornea treatments.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it