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Record W4387007406 · doi:10.32942/x29025

Don’t make genetic data disposable: Best practices for genetic and genomic data archiving

2023· preprint· en· W4387007406 on OpenAlexaff
Deborah M. Leigh, Amy G. Vandergast, Maggie Hunter, Eric D. Crandall, W. Funk, Sean Hoban, Sara J. Oyler‐McCance, Christian Rellstab, Gernot Segelbacher, Chloé Schmidt, Ella Vázquez‐Domínguez, Ivan Paz‐Vinas

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldComputer Science
TopicResearch Data Management Practices
Canadian institutionsUniversity of Manitoba
FundersU.S. Geological SurveyBiodiversa+Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen ForschungNational Science Foundation
KeywordsMetadataData scienceRepurposingGenetic dataBest practiceData managementField (mathematics)Computer scienceGenomicsWorld Wide WebBiologyEcologyData miningGenomePolitical sciencePopulationSociology

Abstract

fetched live from OpenAlex

In ecology and evolution, genetic and genomic data are commonly collected for a vast array of scientific and applied purposes. Despite mandates for public archiving, such data are typically used only once by the data-generating authors. The repurposing of genetic and genomic datasets remains uncommon because it is often difficult, if not impossible, due to non-standard archiving practices and lack of contextual metadata. But as the new research field of macrogenetics is demonstrating, if genetic data and their metadata were more accessible, they could be reused for many additional purposes, far beyond their initial intended impact. In this review, we outline the main challenges with existing genetic and genomic data archives, factors underlying the challenges, and current best practices for archiving genetic and genomic data. Recognising that this is a longstanding issue due to an absence of formal data management training within the research field of ecology and evolution, we highlight key steps that universities, funding bodies, and scientific publishers could take to ensure timely change towards good data archiving.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.118
metaresearch head score (Gemma)0.244
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Reproducibility · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.882
Threshold uncertainty score0.623

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1180.244
Meta-epidemiology (narrow)0.0010.002
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0090.016
Science and technology studies0.0050.015
Scholarly communication0.0280.044
Open science0.0100.011
Research integrity0.0070.012
Insufficient payload (model declined to judge)0.0030.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.426
GPT teacher head0.444
Teacher spread0.019 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designTheoretical or conceptual
DomainReproducibility
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2023
Admission routes1
Has abstractyes

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