‘I Was Only the Impresario – the Managing Director’: J.J.R. Macleod and the Pragmatics of the Discovery and Development of Insulin
Bibliographic record
Abstract
On 7 November 1923, when J.J.R. Macleod announced that he would split his half of the Nobel Prize with J.B. Collip, following F.G. Banting splitting his half of the prize with C.H. Best, a reporter asked Macleod to assess his share in the discovery of insulin. "Oh, I was only the impresario - the managing director," he replied. Whether Macleod deserved the recognition with Banting of the Nobel Committee for the discovery of insulin, it is certainly clear that the discovery, and especially its efficient development into a remarkably effective diabetes treatment, would not have happened without Macleod's knowledge and laboratory research experience. Nor would it have happened without his leadership and, especially, without his acumen as the managing director, or impresario, of the insulin enterprise.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.007 | 0.016 |
| Meta-epidemiology (narrow) | 0.000 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.009 | 0.009 |
| Scholarly communication | 0.010 | 0.006 |
| Open science | 0.001 | 0.002 |
| Research integrity | 0.004 | 0.010 |
| Insufficient payload (model declined to judge) | 0.005 | 0.002 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".