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Endovascular thrombectomy for acute ischaemic stroke with established large infarct: multicentre, open-label, randomised trial
Martin Bendszus, Jens Fiehler, Fabien Subtil, Susanne Bonekamp, Anne Hege Aamodt, Blanca Fuentes, Elke R. Gizewski, Michael D. Hill, Antonı́n Krajina, Laurent Pierot, Claus Z. Simonsen, Kamil Zeleňák, Rolf Ankerlund Blauenfeldt, Bastian Cheng, Angélique Denis, Hannes Deutschmann, Franziska Dorn, Fabian Flottmann, Susanne Gellißen, Johannes Gerber, Mayank Goyal, Jozef Haring, Christian Herweh, Silke Hopf-Jensen, Vi Tuan Hua, Märit Jensen, Andreas Kastrup, C Keil, Andrej Klepanec, Egon Kurča, Ronni Mikkelsen, Markus Möhlenbruch, Stefan Müller‐Hülsbeck, Nico Münnich, Paolo Pagano, Panagiotis Papanagiotou, Gabor C. Petzold, Mirko Pham, Volker Puetz, Jan Raupach, Gernot Reimann, Peter Ringleb, Maximilian Schell, Eckhard Schlemm, Silvia Schönenberger, Bjørn Tennøe, Christian Ulfert, Kateřina Vališ, Eva Vítková, Dominik F. Vollherbst, Wolfgang Wick, Götz Thomalla, Olaf Adamczewski, Kirill Alektoror, März Alexander, Maria Eleni Alexandrou, Quentin Alias, Fadha Elawi Al-Kuzae, Julien Allard, Rahman Al-Schameri, Alberto Álvarez, Grethe Andersen, Rolf AnkerlundBlaufeldt, Riedel Antje, Hannes Appelbohm, Maria Argren, Anne Assmann, Michael Augustin, E Bach, Michal Bar, Maria Barleben, Flore Baronnet, Andrés Barrios, Xénia Bavúzová, Rikke BayThomsen, Sandra Becker, Sylvia Beer, Daniel Behme, Maximilian Bellut, Joachim Berkefeld, Maximillian Bester, Felix J. Bode, Christian Boehme, Ramona Boese, Ferdinand O. Bohmann, Jan Borggrefe, Erendira Gabriela Boss, Maria Boutchakova, Elfi Boxhammer, Annemarie Brandhofe, Michael O. Breckwoldt, Casper Brekenfeld, Alex Brehm, Christian Brem, Stella Breuer, Tobias Breyer, Petra Brodová, Gabriel Broocks, Christoph Brosinski, Nele Bubel, Jiří Búřil, Martin Čábal, Elena de Celis, Emmanuel Chabert, Daniel Charissé, Vendelı́n Chovanec, Peter Cidlinsky, Juraj Cisár, Frédéric Clarençon, Sophie Crozier, Nina Čurdová, Michele Damaskinos, Dorte Damgaard, Martin Daniš, Florian Dazinger, Milani Deb‐Chatterji, Asima Delalic, Agnieszka Delekta, Stephen Delorme, Elie Diamandis, Tove Diedrichsen, Irena Doležalová, Richard du Mesnil de Rochemont, Kristina DupontHougaard, Taraneh Ebrahimi, Florian Eff, Ilona Eliášová, Brian Enriquez, Mostafa Ergawy, Fabian Essig, Maiken Falkesgaard, Simon Fandler‐Höfler, Andrés Fernández, Jean‐Christophe Ferré, Anna Ferrier, Krystian Figlewski, Sebastian Fischer, Urs Fischer, Robert Forbig, Christian Förch, Annette Fromm, Ines Gaedke, Romana Galczak, Malik Galijašević, Bernhard Ganser, Thomas Gattringer, Matthias Gawlitza, Sarah Gelhard, Michail Panagiotis Giannakakis, Karin Gindlhuber, Bernhard Glodny, Tim Godel, Einar Goebell, David Goldemund, Michael Görtler, Astrid Grams, Joachim Gruber, Katharina Gruber, Thomas Günthner‐Lengsfeld, Kathrin Haase, Floriana Hacker-Ivan, Erika Hallerstig, Uta Hanning, Michal Haršány, Ján Haršány, Christian Hartmann, Eva Hassler, Kristina Hauptmann, Karl Georg Häusler, Constantin Hecker, Victoria Hellstern, Hans Henkes, Victoria Hernández, Tim Hilgenfeld, Niels Hjort, Nina HjortJensen, Maya Hoelter, Karl‐Titus Hoffmann, Brigitte Holst, Markus Holtmannspoetter, Julia Hoppe, Susanne Hörner, Leif HougaardSoerensen, Alexander Hubert, Eva Hurtíková, Stanislava Jakubíček, Tanja Janjic, Kirsten Jaramillo, Angela Jedlitschka, Schiela Jensen, Jessica Jesser, Leonie Jestaedt, Sabine Johnson, Tomáš Jonszta, P. Kalmár, Sanja Karabegovic, Kollo Karen, Hopp Katja, Natalia Keeba, Petra Keese, Christina Kefalaykos, Fee Keil, Lars Kellert, Christoph Kellinghaus, Roxane‐Isabelle Kestner, Stefan Kiechl, Monika Killer‐Oberpfalzer, Casjupea Knispel, Michael Knoflach, Sabine Köhler, Konstantin Kohlhase, Alexander M. Kollikowski, Martin Kovář, Michael Kral, Georgi Krastev, Lars Udo Krause, Rudolf Kreidenhuber, Tomáš Křivka, Adam Krkoška, Jan Robert Kröger, Moritz Kronlage, Paweł Krukowski, Julia Kühn, Natalia Kurka, Michael Kuschnerow, Rita Lachmund, Susanne Lamprecht, Rüdiger Lange, Monika Lauer, Alonso de Leciñana, Sara Leder, Anne Léger, Nils Lehnen, Dominik Lehrieder, Maximilian Leißner, Markus Leitinger, Ursula Leitner, Stéphanie Lenck, Eva Lenzenweger, Thomas Liebig, Stephan Lowens, Manuel Lunzer, Christian Maegerlein, Marton Magyar, Leonardo Marques, David Matyáš, Matthias Mauritz, Thormann Maximilian, Lukas Mayer-Süß, Stephan Meckel, Oldřich Medek, Julius N. Meißner, Pavel Mencl, Andrea Merkle, Birte Mesche, Dominik Michalski, Robert Mikulík, Boris Modrau, Alexander Mohr, Christoph Mönninghoff, Tobias Moser, Ramona Mücke, Erasmia Broussalis, Sebastian Mutzenbach, Pedro Navía, Ulf Neuberger, Hermann Neugebauer, Jens Neumann, Anh Nguyên, Kurt Niederkorn, Vladimír Nosáľ, Richard Novobilský, Nikos Ntoulias, Lukas Nussbaum, Joanna Oder, Andreas Oldag, Marián Ondrejkovič, Ferdinand Otto, Dagmar Otto, Daniel Paech, Lars‐Peder Pallesen, Michal Panský, Samp Patrick, Harald Paukisch, Johann Pelz, Inga Petersen, Martina Petersen, Johannes Pfaff, Waltraud Pfeilschifter, Alexander Pichler, Slaven Pikija, Jan PlougmannPovlsen, Christoph Polkowski, Nenad Polomac, Rupert Horst Portugaller, Marika Poulsen, Michael Preiß, Kévin Premat, Sjur Prestsæter, Rocío Prieto‐Pérez, Marios Psychogios, Jan Purrucker, Heike Rai, Maximilian Rauch, G. Reimann, Sarah C. 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Sporns, Michael Städt, Eike Steidl, Anne Margrethe Kaalaas Størdal, Sebastian Stösser, Sarah Strickmann, Ondřej Strýček, Igor Suškevič, Ján Sýkora, Daniela Thaler, Sara Theisen, Petar Trendafilov, Johannes Trenkler, Christoph Trumm, Ioannis Tsogkas, Jon‐Anders Tunold, Lars Tveit, Jiří Vaníček, Christine Vassilev, Heinz-Leonhard Voit-Höhne, Bohuslav Vojtíšek, Karoline Volderauer, Christoph Vollmuth, Kamila Volna, Ondřej Volný, Poul VonWeitzel-Mudersbach, Martin Vorčák, Marlies Wagner, Gaute Kjellevold Wathle, Werner Weber, Anushe Weber, Viktor Weiss, Johannes Weller, Katharina Wenger-Alakmeh, Cyrill Weyland, Friedrich Weymayr, Ulrike Wießpeiner, Johannes Willeit, Aymeric Wittwer, Frank A. Wollenweber, Ginette Wortmann, Silke Wunderlich, Yanyan Xiong, Se-Jong You, Lasse ZachoSpeiser, Jana Zeleňáková, Seraphine Zubel
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
Bibliographic record
VenueThe Lancet · 2023
Typearticle
Languageen
FieldMedicine
TopicAcute Ischemic Stroke Management
Canadian institutionsFoothills Medical CentreUniversity of Calgary
FundersHORIZON EUROPE Framework Programme
KeywordsMedicineIschaemic strokeStroke (engine)Open labelAcute strokeEndovascular treatmentRandomized controlled trialClinical trialSurgeryInternal medicineTissue plasminogen activatorIschemiaAneurysm
Abstract
No abstract in any covered source. Its absence is recorded, not treated as a negative.
No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.410
Threshold uncertainty score0.674
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
Opus teacher head0.045
GPT teacher head0.335
Teacher spread0.290 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itQuick stats
Citations442
Published2023
Admission routes1
Has abstractno