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Record W4387540944 · doi:10.21203/rs.3.rs-3414056/v1

Kidney volume normative values in Central European children aged 0-19 years – a multicenter study

2023· preprint· en· W4387540944 on OpenAlexaff
Łukasz Obrycki, Jędrzej Sarnecki, Michał Pac, Marianna Lichosik, Małgorzata Sopińska, Małgorzata Placzyńska, Joanna Milart, Małgorzata Stańczyk, Julia Mirecka, Agnieszka Wasilewska, Maciej Michalski, Weronika Lewandowska, Tadeusz Dereziński, Terezie Šuláková, David A. Supik, Andrius Čekuolis, Renata Vitkevič, Aldona Wierzbicka, Jan Koziej, Krzysztof Skoczyński, Jan Horubała, Augustina Jankauskienė, Bolesław Kalicki, Katarzyna Jobs, Marcin Tkaczyk, Mieczysław Litwin

Bibliographic record

VenueResearch Square · 2023
Typepreprint
Languageen
FieldHealth Professions
TopicGlobal Health Care Issues
Canadian institutionsChildren's Hospital of Eastern Ontario
Fundersnot available
KeywordsNormativeVolume (thermodynamics)Multicenter studyMedicineInternal medicinePolitical sciencePhysicsLawThermodynamics

Abstract

fetched live from OpenAlex

Abstract Background and Objecitves: The currently available kidney volume normative values in children are restricted to small populations from single-centre studies not assessing kidney function and including none or only a small number of adolescents. This study aimed to obtain ultrasound-based kidney volume normative values derived from a large European Caucasian paediatric population with normal kidney function. Methods: After recruitment of 1427 children aged 0–19 years, 1396 individuals with no history of kidney disease and normal estimated glomerular filtration rate were selected for the sonographic evaluation of kidney volume. Kidney volume was correlated with age, height, weight, body surface area and body mass index. Kidney volume curves and tables related to anthropometric parameters were generated using the LMS method. Kidney volume predictors were evaluated using multivariate regression analysis with collinearity checks. Results: No clinically significant differences in kidney volume in relation to height were found between males and females, between supine and prone position and between left and right kidneys. Males had, however, larger age-related kidney volumes than females in most age categories. For the prediction of kidney volume, the highest coefficient correlation was observed for body surface area (r = 0.94), followed by weight (r = 0.92), height (r = 0.91), age (r = 0.91), and body mass index (r = 0.67; p < 0.001 for all). Conclusions: This study presents LMS-percentile curves and tables for kidney volume which can be used as reference values for children aged 0–19 years.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0020.002
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.155
GPT teacher head0.532
Teacher spread0.377 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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