MétaCan
Menu
Back to cohort
Record W4387701111 · doi:10.1093/evlett/qrad048

The evolution of genetic covariance and modularity as a result of multigenerational environmental fluctuation

2023· article· en· W4387701111 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueEvolution Letters · 2023
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicEvolution and Genetic Dynamics
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsCovarianceSelection (genetic algorithm)PleiotropyTraitPopulationBiologyEvolutionary biologyCMA-ESQuantitative geneticsDisruptive selectionModularity (biology)Genetic driftCovariance functionMathematicsNatural selectionGenetic variationStatisticsGeneticsComputer scienceArtificial intelligencePhenotype

Abstract

fetched live from OpenAlex

Abstract The genetic covariance between traits can affect the evolution of a population through selection, drift, and migration. Conversely, research has demonstrated the reciprocal effect of evolutionary processes on changing genetic covariances, in part through mutational covariance, correlational selection, and plasticity. In this article, we propose that correlated changes in selective optima over generations can cause the evolution of genetic covariance and the G-matrix in such a way that the population can, in the future, evolve faster. We use individual-based simulations of populations exposed to three types of changing environments that differ in the correlation of the change between selective pressures. Our simulation experiments demonstrate that selection pressures for different traits changing in a correlated pattern over generations can lead to stronger trait correlations compared to the case with independently changing selective optima. Our findings show that correlated selective pressures result in significantly higher genetic trait covariance and that pleiotropy accounts for the majority of the difference in covariance between treatments. We also observe that the mutational variance evolves according to the environment that the populations were exposed to. Moreover, we show that clustered patterns of changes in selection can allow the evolution of genetic modularity. We show that the pattern of change in the selective environment affects the pace at which fitness evolves, with populations experiencing correlated change in optima having on average higher mean fitness than those experiencing uncorrelated environment change.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.912
Threshold uncertainty score0.338

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.004
GPT teacher head0.211
Teacher spread0.207 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it