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S3571 A Rare Case of Raoultella ornithinolytica Bacterial Infection in Liver Cirrhosis Patient

2023· article· en· W4387751498 on OpenAlexaboutno aff
Khandokar Talib, Khadija Raza, Ibrar Atiq, Tasnima Elahi, Ali Marhaba

Bibliographic record

VenueThe American Journal of Gastroenterology · 2023
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicVibrio bacteria research studies
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineCirrhosisGastroenterologyInternal medicineEsophageal varicesAscitesSurgeryPortal hypertension

Abstract

fetched live from OpenAlex

Introduction: Infection with Raoultella ornitholytica is rare and this Gram-negative, oxidase-negative, non-motile, capsulated facultative anaerobic bacillus of the Enterobacteriacae family is generally found in aquatic environments, fish, and insects. Raoultella ornitholytica occurs mainly in patients with underlying malignancies or chronic diseases, trauma, nosocomial infection, and invasive procedures and is a risk factor for a poor outcome. The bacterium was originally named Klebsiella ornitholytica but was reclassified as Raoultella ornitholytica. Case Description/Methods: 68 y.o. man with a known history of alcoholic liver cirrhosis with grade 2 esophageal varices, CAD status post-PCI, essential hypertension, hyperlipidemia, and GERD presented to the emergency room after being advised by an outside hospital following positive blood cultures. He had recently visited Canada, where he presented to a local emergency room with chills and confusion, was diagnosed with a urinary tract infection, and was subsequently treated with antibiotics. He denied any seafood ingestion or heavy alcohol intake at the time (Figure 1). Upon presentation, he was noted to have significant worsening of ascites and confusion. Initial vitals and labs met septic criteria. CT abdomen and pelvis revealed liver cirrhosis, esophageal varices, and significant ascites. Paracentesis performed was indicative of SBP. The ascitic fluid culture was negative possibly as the patient was already on antibiotics. Blood cultures reported from the outside hospital were positive for Raoultella ornitholytica and sensitive to cefazolin and TMP/SMX but resistant to ampicillin. The repeat blood cultures here were negative. The patient underwent EGD which demonstrated Grade II esophageal varices with no stigmata of recent bleeding, and congestive gastropathy due to portal hypertension. Plan was to repeat EGD in 1 year. The patient was stabilized after resuscitative measures and antibiotics. He was discharged home after a few days of hospitalization with cefazolin and metronidazole. Discussion: Raoultella ornitholytica is an emerging bacterium with potent virulence. It is very rare in the case of liver cirrhosis patients but should be dealt with attention.Figure 1.: EGD demonstrated Grade II esophageal varices with no signs of recent bleeding.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.016

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0030.001
Scholarly communication0.0010.002
Open science0.0010.001
Research integrity0.0030.002
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.267
Teacher spread0.255 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2023
Admission routes1
Has abstractyes

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