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When Does Schizophrenia Begin?

2005· book-chapter· en· W4388154280 on OpenAlexaff
Peter Williamson

Bibliographic record

Venuenot available
Typebook-chapter
Languageen
FieldArts and Humanities
TopicMental Health and Psychiatry
Canadian institutionsWestern University
Fundersnot available
KeywordsSchizophrenia (object-oriented programming)PsychologyBrain developmentSynaptic pruningDevelopmental psychologyPsychiatryNeuroscienceMedicine

Abstract

fetched live from OpenAlex

Abstract While the hallucinations, delusions, and other symptoms of schizophrenia begin in most patients by the end of adolescence or early adulthood, there is evidence to suggest that the illness actually begins long before this. This chapter will review some of the observations leading us to believe that schizophrenia arises from defects in early brain development in the womb or in later brain development perhaps involving cortical pruning at adolescence. Some of the arguments for an early neurodevelopmental origin will be reviewed, followed by a discussion of likely locations for the defect and some of the possible causes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.009
Threshold uncertainty score0.029

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0010.002
Scholarly communication0.0020.003
Open science0.0000.001
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0090.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.029
GPT teacher head0.236
Teacher spread0.206 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2005
Admission routes1
Has abstractyes

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