Small airways obstruction is present in Covid-19 pneumonia’s acute period.
Bibliographic record
Abstract
The role of small airways in the pathogenesis of SARS-CoV-2 induced lung disease has not been sufficiently studied. Especially it concerns the acute period of disease. The aim of our study was to find out whether small airways obstruction occurs in acute period of covid-19 infection and whether obstruction resolves within three months. We selected 18 oxygen dependent patients treated in the hospital for moderate severity covid-19 pneumonia who arrived for control three months after the discharge. Small airways patency was measured by forced oscillation technique (FOT) using portable instrument Tremoflo C-100, Thorasys, Canada. Indices characterizing small airways resistance and reactance are present in the table. During the acute period the upper limit of normal (ULN) for resistance and reactance indices was exceeded in 11 of 18 patients, but after 3 months – only in 4 to 5 of 18. M & CI – mean and confidence interval; ULN – upper limit of normal We conclude that small airways become obstructed during acute period of covid-19 pneumonia. This condition resolves in 3 months in majority of patients, however one third of patients still have signs of small airways disease after 3 months recovery period.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".